Florence Santa Maria Novella to Palermo Centrale train with Intercity Notte

Sat 05 Sept
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2,000+ travel companies
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The cheapest and fastest trains from Florence Santa Maria Novella to Palermo Centrale

Showing times, prices and bookable tickets for 05 Sept

Cheapest price on 05 Sept

£119

Average ticket price on 05 Sept

£134

Fastest journey on 05 Sept

12 h 48 m

Average journey duration on 05 Sept

13 h 57 m

Trains on 05 Sept

7

Distance

655 km

Cheap tickets

The best way to find a cheap train ticket from Florence Santa Maria Novella to Palermo Centrale is to book your journey as far in advance as possible and to avoid travelling at rush hour.

The average ticket from Florence Santa Maria Novella to Palermo Centrale will cost around £134 if you buy it on the day, but you can find cheap train tickets today for only £119.

Fast trains

To travel from Florence Santa Maria Novella to Palermo Centrale you need to make at least one change.

  • IntercityIntercity 581 · Intercity 551 · Intercity 727
    5:4517h17
    Florence Santa Maria Novella
    23:02Palermo Centrale
    £1191One-way
    2 changes
  • FrecciarossaFRECCIAROSSA 9503+IntercityIntercity 723
    6:0013h10
    Florence Santa Maria Novella
    19:10Palermo Centrale
    £1261One-way
    1 change
  • FrecciarossaFRECCIAROSSA 9519+IntercityIntercity 727
    10:1412h48
    Florence Santa Maria Novella
    23:02Palermo Centrale
    £1261One-way
    1 change
  • RegionaleRegionale 18781+IntercityIntercity 594+Intercity NotteInterCityNotte 1959
    18:2217h36
    Florence Santa Maria Novella
    11:58Palermo Centrale
    £1271One-way
    2 changes
  • FrecciarossaFRECCIAROSSA 9435+Intercity NotteInterCityNotte 1959
    20:4815h10
    Florence Santa Maria Novella
    11:58Palermo Centrale
    £1371One-way
    1 change

Travel Information

Compare train, coach, flight and ferry for Florence Santa Maria Novella to Palermo Centrale

Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Palermo Centrale among Omio's users. If you are prioritising price, take the ferry, with an average ticket price of £39 For those with little time, consider booking a flight, which has an average total journey time of 3h 35m. Average ticket prices depend on the travel mode: a ferry costs an average of £39, while a train costs an average of £104.

Distance: 655 km

Compare train with

Most popular
Train
Coach
Flight
Ferry
Driving

£104

Average Price

£88

Average Price

£74

Average Price

£39

Average Price

Cheapest

£57

Average Price

(fuel + tolls)

13h 9m

Average total duration

12h 39m

Onboard

+

30m

Additional time*

16h 47m

Average total duration

16h 17m

Onboard

+

30m

Additional time*

3h 35m

Average total duration

Fastest

1h 35m

Onboard

+

2h 0m

Additional time*

21h 0m

Average total duration

20h 0m

Onboard

+

1h 0m

Additional time*

24h 14m

Average total duration

(door-to-door)

Intercity Notte

Most popular train company

FlixBus

Most popular bus company

Malta Air

Most popular airline

Grimaldi

Most popular ferry company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence Santa Maria Novella to Palermo Centrale is a ferry with an average price of £39.

This is compared to other travel options from Florence Santa Maria Novella to Palermo Centrale:

A ferry is £35 less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Palermo Centrale costing on average £74.

A ferry is £49 less than a coach for this route with tickets for a coach from Florence Santa Maria Novella to Palermo Centrale costing on average £88.

A ferry is £65 less than a train for this route with tickets for a train from Florence Santa Maria Novella to Palermo Centrale costing on average £104.

The fastest way to travel from Florence Santa Maria Novella to Palermo Centrale is by flight with an average journey time of 1h 35m.

Other travel options to Palermo Centrale take longer:

Train takes on average 12h 39m.

Coach takes on average 16h 17m.

Ferry takes on average 20h 0m.

It's helpful to compare your options as there are 4 ways to travel between Florence Santa Maria Novella and Palermo Centrale including taking a train, coach, flight and ferry.
Take the train. It's meaningfully faster than driving, and the time saved usually justifies the price.

You'll arrive about 11h 35m sooner (12h 39m by train vs 24h 14m by car). Tickets start at around £104 compared to roughly £57 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.

Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.

Live departures

Florence Santa Maria Novella to Palermo Centrale train times

The table below shows live departures for Florence Santa Maria Novella to Palermo Centrale trains for tomorrow, Saturday 5 September. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesChanges
Tickets
IntercityIntercity 581 · Intercity 551 · Intercity 7275:45 Florence Santa Maria Novella
17h17
23:02 Palermo Centrale2 changes
FrecciarossaFRECCIAROSSA 9503+IntercityIntercity 7236:00 Florence Santa Maria Novella
13h10
19:10 Palermo Centrale1 change
FrecciarossaFRECCIAROSSA 9519+IntercityIntercity 72710:14 Florence Santa Maria Novella
12h48
23:02 Palermo Centrale1 change
RegionaleRegionale 18781+IntercityIntercity 594+Intercity NotteInterCityNotte 195918:22 Florence Santa Maria Novella
17h36
11:58 Palermo Centrale2 changes
FrecciarossaFRECCIAROSSA 8525+Intercity NotteInterCityNotte 195518:33 Florence Santa Maria Novella
14h40
9:13 Palermo Centrale1 change
FrecciarossaFRECCIAROSSA 9555 · FRECCIAROSSA 9653+Intercity NotteInterCityNotte 195519:14 Florence Santa Maria Novella
13h59
9:13 Palermo Centrale2 changes
FrecciarossaFRECCIAROSSA 9435+Intercity NotteInterCityNotte 195920:48 Florence Santa Maria Novella
15h10
11:58 Palermo Centrale1 change

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence Santa Maria Novella to Palermo Centrale by train, coach, flight or ferry

Compare train, coach, flight and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
05 Sept
Sun
06 Sept
Mon
07 Sept
Tue
08 Sept
Wed
09 Sept
Thu
10 Sept
Fri
11 Sept

Why should you book Florence Santa Maria Novella to Palermo Centrale trains with Omio?

Intercity Notte as well as Intercity, Italo, Frecciargento, Frecciarossa and more offer trains services from Florence Santa Maria Novella to Palermo Centrale.
Omio is the only official third party seller for Intercity Notte tickets.

Why book with Omio vs Intercity Notte?

  • Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo, Frecciargento or Frecciarossa to find the best option for your trip from Florence Santa Maria Novella to Palermo Centrale.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Florence Santa Maria Novella to Palermo Centrale.

Journey information

Overview: Train from Florence Santa Maria Novella to Palermo Centrale

ItalyItaly
ItalyItaly
Icon of train

Trains from Florence Santa Maria Novella to Palermo Centrale run on average 6 times per day, taking around 12h 39m. Cheap train tickets for this journey start at £73 but you can travel from only £17 by flight.

The earliest train runs at 01:13, the last at 22:40. The fastest train covers the 655 km distance in 12h 47m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £17
Distance
655 km
Average train duration
12h 39m
Cheapest ticket price
£73
Trains per day
6
Fastest train
12h 47m
First train
1:13
Last train
22:40
Cheapest Month
Feb
Cheapest Day
Wed
High Season
Apr - Jun
Low Season
Oct - Dec
Busiest Day
Wed
Least Busy Day
Thu
Best time to book
1 day
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £17

Train companies: Intercity Notte, Intercity, Italo, Frecciargento, Frecciarossa from Florence Santa Maria Novella to Palermo Centrale trainsIntercity Notte, Intercity, Italo, Frecciargento, Frecciarossa trains will get you between Florence Santa Maria Novella and Palermo Centrale from £17. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Intercity Notte

About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Intercity Notte frequency
3 a day
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone

Intercity

About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Intercity Duration
15h 57m
Cheapest Intercity Price
£73
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone

Italo

About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Italo Duration
14h 7m
Cheapest Italo Price
£95
Italo frequency
1 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Learn more about Italo

Frecciargento

About
Frecciargento is a high-speed train service operated by Trenitalia, the national railway company of Italy. It runs on the most popular routes throughout the country, connecting major cities such as Rome, Milan, Florence, and Venice. Frecciargento trains offer a comfortable and convenient way to travel, with a range of ticket types available, including Economy, Standard, and Business. Onboard facilities include air-conditioning, power sockets, and free Wi-Fi. Frecciargento trains are fast and reliable, with journey times of up to four hours between Rome and Milan. They are a great way to explore Italy in style and comfort.
Luggage & cancellation policy
Average Frecciargento Duration
15h 37m
Cheapest Frecciargento Price
£91
Luggage included
1 carry-on bag and 1 piece of luggage included
Luggage storage
Overhead racks, luggage areas at end of carriages, between seats
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Bar-bistro service with snacks, drinks, and light meals. At-seat service in First Class
Seat reservation
Seat reservation included in ticket price for all classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone

Frecciarossa

About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Frecciarossa Duration
12h 47m
Cheapest Frecciarossa Price
£80
Frecciarossa frequency
1 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Learn more about Frecciarossa

FAQs: Florence Santa Maria Novella to Palermo Centrale train

Find answers to the most common questions about traveling from Florence Santa Maria Novella to Palermo Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo Centrale, this guide helps you travel smarter and with confidence.

FAQs
The cost of a train ticket from Florence Santa Maria Novella to Palermo Centrale can vary. The cheapest tickets are usually available from £73, while the average price tends to be around £104.
The train journey from Florence Santa Maria Novella to Palermo Centrale covers a distance of 655 km and takes approximately 12h 47m. Trains run 6 per day.
The train distance from Florence Santa Maria Novella to Palermo Centrale is 655 km.
The first train from Florence Santa Maria Novella to Palermo Centrale leaves at 1:13.
The last train from Florence Santa Maria Novella to Palermo Centrale departs at 22:40.
Trains from Florence Santa Maria Novella to Palermo Centrale run approximately 6 times per day.
Yes, there is a high-speed train service from Florence Santa Maria Novella to Palermo Centrale.
Unfortunately, there is no direct train service currently available from Florence Santa Maria Novella to Palermo Centrale.
To get from Florence Santa Maria Novella to Palermo Centrale, you can choose from several travel options including train, coach, flight and ferry.
Yes, there is a night train from Florence Santa Maria Novella to Palermo Centrale.
The cheapest way to get from Florence Santa Maria Novella to Palermo Centrale is by flight, costing approximately £17.
Booking trains from Florence Santa Maria Novella to Palermo Centrale in advance is advisable, especially during peak travel seasons or for long journeys, to ensure availability and secure better fares.
Yes, the train journey from Firenze Santa Maria Novella to Palermo Centrale is scenic, offering picturesque views of the Italian countryside, coastal landscapes, and charming towns along the way.
A day trip from Firenze Santa Maria Novella to Palermo Centrale is not feasible as the journey takes 12h 47m and trains operate 6 times per day over a distance of 655 km.
Yes, you can take the train from Florence Santa Maria Novella to Palermo Centrale.

popular train stations

Important Stations and Airports in Florence Santa Maria Novella and Palermo Centrale

Most Florence Santa Maria Novella to Palermo Centrale trains use the Firenze Santa Maria Novella to Enna station pair. Use this guide to compare Florence Santa Maria Novella and Palermo Centrale train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Florence
Arrival train stations in Sicily
Firenze Santa Maria NovellaPiazza della Stazione, 1, 50123 Florence, Italy+39 0552352595WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
City-centre transport

Getting to Firenze Santa Maria Novella from Florence city centre

Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:

TramT2 · 4m · £2 · every ~21 min

Firenze Santa Maria Novella train station facilities and services

Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.

Food and drink

Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more

Wi-Fi and ATMs

Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.

Tickets and information

The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.

Luggage and lost property

Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.

Parking, taxis and toilets

Available at Firenze Santa Maria Novella: Parking, Taxis, WC.

Bike and car services

Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.

Shops, hotels and contact

Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.

More about Firenze Santa Maria Novella

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HomeTrainsTrains in ItalyFlorence Santa Maria Novella to Palermo Centrale train

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