The cheapest and fastest trains from Florence Santa Maria Novella to Palermo Centrale
Cheapest price
£119
Average price
£134
Fastest journey
12 h 47 m
Average duration
16 h 4 m
Trains per day
5
Distance
655 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Palermo Centrale is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Florence Santa Maria Novella to Palermo Centrale will cost around £134 if you buy it on the day, but you can find cheap train tickets today for only £119.
To travel from Florence Santa Maria Novella to Palermo Centrale you need to make at least one change.
Regionale 18251+
Intercity 723+
InterCityNotte 8990:4018h32Florence Santa Maria Novella19:12Palermo Centrale£1191One-way2 changes
Regionale 18251+
Intercity 723+
InterCityNotte 8990:4018h32Florence Santa Maria Novella19:12Palermo Centrale£1201One-way2 changes
Intercity 581 · Intercity 551 · Intercity 7275:4517h16Florence Santa Maria Novella23:01Palermo Centrale£1351One-way2 changes
FRECCIAROSSA 9519+
Intercity 72710:1412h47Florence Santa Maria Novella23:01Palermo Centrale£1451One-way1 change
FRECCIAROSSA 9503+
Intercity 7236:0013h12Florence Santa Maria Novella19:12Palermo Centrale£1501One-way1 change
FRECCIAROSSA 9519+
Intercity 72710:1412h47Florence Santa Maria Novella23:01Palermo Centrale£1451One-way1 change
FRECCIAROSSA 9503+
Intercity 7236:0013h12Florence Santa Maria Novella19:12Palermo Centrale£1501One-way1 change
Intercity 581 · Intercity 551 · Intercity 7275:4517h16Florence Santa Maria Novella23:01Palermo Centrale£1351One-way2 changes
Regionale 18251+
Intercity 723+
InterCityNotte 8990:4018h32Florence Santa Maria Novella19:12Palermo Centrale£1201One-way2 changes
Regionale 18251+
Intercity 723+
InterCityNotte 8990:4018h32Florence Santa Maria Novella19:12Palermo Centrale£1191One-way2 changes
Travel Information
Compare train, coach, flight and ferry for Florence Santa Maria Novella to Palermo Centrale
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Palermo Centrale among Omio's users. If you are prioritising price take the ferry with prices starting from £44. For those with little time consider booking a flight which can get you there in 1h 42m. The ticket price range depends on the travel mode: a ferry costs an average of £44, and a train costs an average of £77.
Distance: 655 km
Compare train with
Most popular Train | Coach | Flight | Ferry |
|---|---|---|---|
£116 Average Price | £55 Average Price | £79 Average Price | £49 Average Price Cheapest |
13h 10m Average total duration 12h 40m Onboard + 30m Additional time* | 16h 47m Average total duration 16h 17m Onboard + 30m Additional time* | 4h 42m Average total duration Fastest 1h 42m Onboard + 3h 0m Additional time* | 21h 0m Average total duration 20h 0m Onboard + 1h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Palermo Centrale train times
The table below shows live departures for Florence Santa Maria Novella to Palermo Centrale trains for tomorrow, Wednesday 22 July. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
Intercity 723+ Regionale 18251+ InterCityNotte 899 | 0:40 Florence Santa Maria Novella | 18h32 | 19:12 Palermo Centrale | 2 changes | |
Intercity 723+ Regionale 18251+ InterCityNotte 899 | 0:40 Florence Santa Maria Novella | 18h32 | 19:12 Palermo Centrale | 2 changes | |
Intercity 581 · Intercity 551 · Intercity 727 | 5:45 Florence Santa Maria Novella | 17h16 | 23:01 Palermo Centrale | 2 changes | |
FRECCIAROSSA 9503+ Intercity 723 | 6:00 Florence Santa Maria Novella | 13h12 | 19:12 Palermo Centrale | 1 change | |
FRECCIAROSSA 9519+ Intercity 727 | 10:14 Florence Santa Maria Novella | 12h47 | 23:01 Palermo Centrale | 1 change |
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Palermo Centrale by train, coach, flight or ferry
Compare train, coach, flight and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
22 Jul
23 Jul
24 Jul
25 Jul
26 Jul
27 Jul
28 Jul
Why should you book Florence Santa Maria Novella to Palermo Centrale trains with Omio?
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo, Frecciargento or Frecciarossa to find the best option for your trip from Florence Santa Maria Novella to Palermo Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Florence Santa Maria Novella to Palermo Centrale.
Journey information
Overview: Train from Florence Santa Maria Novella to Palermo Centrale
Trains from Florence Santa Maria Novella to Palermo Centrale run on average 6 times per day, taking around 12h 40m. Cheap train tickets for this journey start at £77 but you can travel from only £15 by coach.
The earliest train runs at 03:35, the last at 23:40. The fastest train covers the 655 km distance in 12h 44m.
Distance 655 km |
Average train duration 12h 40m |
Cheapest ticket price £77 |
Trains per day 6 |
Fastest train 12h 44m |
First train 3:35 |
Last train 23:40 |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Mon |
Train companies: Intercity Notte, Intercity, Italo, Frecciargento, Frecciarossa from Florence Santa Maria Novella to Palermo Centrale trainsIntercity Notte, Intercity, Italo, Frecciargento, Frecciarossa trains will get you between Florence Santa Maria Novella and Palermo Centrale from £15. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Intercity
Italo
Frecciargento
Frecciarossa
FAQs: Florence Santa Maria Novella to Palermo Centrale train
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Palermo Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Florence Santa Maria Novella and Palermo Centrale
Most Florence Santa Maria Novella to Palermo Centrale trains use the Firenze Santa Maria Novella to Enna station pair. Use this guide to compare Florence Santa Maria Novella and Palermo Centrale train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Firenze Santa Maria Novella from Florence city centre
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella train station facilities and services
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental and Information Desk.
Food and drink
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Wi-Fi and ATMs
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
Tickets and information
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Parking, taxis and toilets
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Bike and car services
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.



