- Must visit
Archaeological Museum of Mytilene
Archaeological museum with mosaics, sculpture and finds from ancient Lesbos. Essential for understanding the island’s long history.
Cheapest price on 23 Oct
£130
Average ticket price on 23 Oct
£176
Fastest journey on 23 Oct
1 h 5 m
Average journey duration on 23 Oct
8 h 46 m
Flights on 23 Oct
4
Distance
352 km
The best way to find a cheap flight ticket from Thessaloniki to Mytilene is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Thessaloniki to Mytilene will cost around £176 if you buy it on the day, but you can find cheap flight tickets today for only £130.
On Fri 23 Oct, we found 4 flights from Thessaloniki to Mytilene, including 2 direct services.
These direct flights cover the 352 km distance in an average of 8 h 46 m but if you time it right, some flights will get you there in just 1 h 5 m .
The slowest flights will take 1 d 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
A3586
GQ500
GQ391 · GQ300
GQ391 · GQ302
GQ500
A3586
GQ391 · GQ302
GQ391 · GQ300Flights from Thessaloniki to Mytilene depart on average 7 times per day, taking around 1h 46m. Cheap flight tickets for this journey start at £63 but you can travel from only £33 by ferry.
There are 1 flights per day. The earliest flight runs at 01:25, the last at 23:40. The fastest flight covers the 352 km distance in 1h 0m. October is the cheapest month to fly.
Distance 352 km |
Average flight duration 1h 46m |
Cheapest ticket price £63 |
Flights per day 7 |
Direct flights 1 |
Fastest flight 1h 0m |
First flight 1:25 |
Last flight 23:40 |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Jul - Sept |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 21 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Thessaloniki to Mytilene.
The table below shows live departures for Thessaloniki to Mytilene flights for today, Thursday 22 October. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
GQ389 · GQ300 | 22:10 Thessaloniki International Airport | 9h35 | 7:45 Mytilene International Airport | 1 change | |
GQ389 · GQ302 | 22:10 Thessaloniki International Airport | 16h55 | 15:05 Mytilene International Airport | 1 change | |
GQ389 · GQ304 | 22:10 Thessaloniki International Airport | 23h10 | 21:20 Mytilene International Airport | 1 change | |
| Friday 23 October | |||||
GQ391 · GQ300 | 7:00 Thessaloniki International Airport | 24h45 | 7:45 Mytilene International Airport | 1 change | |
GQ302 · GQ391 | 7:00 Thessaloniki International Airport | 8h05 | 15:05 Mytilene International Airport | 1 change | |
A3586 | 14:00 Thessaloniki International Airport | 1h10 | 15:10 Mytilene International Airport | 0 changesdirect | |
GQ500 | 17:15 Thessaloniki International Airport | 1h05 | 18:20 Mytilene International Airport | 0 changesdirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Mytilene — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mytilene trip today.
Archaeological museum with mosaics, sculpture and finds from ancient Lesbos. Essential for understanding the island’s long history.
Former industrial olive-oil site presenting Lesbos’s production history with machinery and exhibits. Insightful and distinctive local heritage museum.
Compact museum devoted to Theophilos, showing works linked to Greek folk painting and island life. A rewarding stop for art lovers.
Historic harbour district with narrow lanes, old houses and sea views. Popular for walking and getting a feel for traditional Mytilene.
Central square lined with civic buildings and daily city life. A practical and atmospheric base for exploring the old centre on foot.
Main shopping and strolling street with arcades, local shops and lively urban character. Ideal for an easy walk through the heart of town.
Salt-cured sardines from the Gulf of Kalloni, prized on Lesvos for their rich flavour and long fishing tradition. Usually served simply with lemon and olive oil.
Anise-flavoured spirit closely associated with Lesvos, especially Plomari. It is the island’s signature drink and a classic companion to meze.
Local meze of grilled or pan-fried octopus, common in seaside tavernas. It reflects the island’s strong fishing culture and Aegean flavours.
Refined restaurant serving modern Greek cooking with local ingredients in an elegant harbourfront setting suited to a longer evening meal.
Popular traditional taverna known for Lesvian meze, seafood and ouzo in a relaxed local setting near the waterfront.
Established fish taverna focusing on fresh seafood and classic island dishes, with a straightforward atmosphere favoured by locals and visitors.
Moderate for Greece: tavernas and buses are reasonable, but summer rooms and seafront dining cost more than on less touristy islands.
Service is usually included. Round up or leave 5-10% in restaurants for good service; round up taxi fares; small change is fine in cafés.
Find answers to the most common questions about traveling from Thessaloniki to Mytilene by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Mytilene, this guide helps you travel smarter and with confidence.

Most Thessaloniki to Mytilene flights use the Thessaloniki International Airport to Mytilene International Airport airport pair. Use this guide to compare Thessaloniki and Mytilene airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Thessaloniki International Airport is 1 km from Thessaloniki city centre. Public transport options include:
Thessaloniki International Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the arrivals and departures areas.
Lost and found is available at the station.
Available at Thessaloniki International Airport: Parking, Taxis, WC.
Accessibility facilities are available at Thessaloniki International Airport: Ramps, assistance.
Mytilene International Airport is 3 km from Mytilene city centre. Public transport options include:
Mytilene International Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the terminal.
Lost and found is available at the station.
Available at Mytilene International Airport: Parking, Taxis, WC.
Accessibility facilities are available at Mytilene International Airport: Ramps, toilets.
See which airports are used for flights between Thessaloniki and Mytilene, including airport details.
Here are some other resources that might have the information you need