Siena to Lyon bus with FlixBus

Thu 16 Apr
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FlixBus
Curcio Viaggi
Itabus
National Express
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2,000+ travel companies
FlixBus
Curcio Viaggi
Itabus
National Express
Alsa
2,000+ travel companies
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The cheapest and fastest coaches from Siena to Lyon

Showing times and prices for 17 Apr

Cheapest price

£23

Average price

£92

Fastest journey

12 h

Average duration

13 h 18 m

Buses per day

8

Distance

580 km

Cheap tickets

The best way to find a cheap coach ticket from Siena to Lyon is to book your journey as far in advance as possible and to avoid travelling at rush hour.

The average ticket from Siena to Lyon will cost around £92 if you buy it on the day, but you can find cheap coach tickets today for only £23.

Fast coaches

Of the 8 buses that leave Siena for Lyon every day 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

These direct buses cover the 580 km distance in an average of 13 h 18 m but if you time it right, some buses will get you there in just 12 h .

The slowest buses will take 14 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Itabus2126 · 3092
    10:5513h30
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    0:25Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    £231One-way
    1 change
  • Itabus3811 · 3898
    17:5519h00
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    12:55Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    £491One-way
    1 change
  • FlixBusFlixBus
    17:2513h05
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    6:30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    £941One-way
    0 changes
  • FlixBusFlixBus · FlixBus
    0:4513h25
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    14:10Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    £961One-way
    1 change
  • FlixBusFlixBus · FlixBus · FlixBus
    10:4015h45
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    2:25Lyon
    £1021One-way
    2 changes

Travel Information

Compare train, coach and flight for Siena to Lyon

Omio recommends booking the coach as it is the most popular option from Siena to Lyon among Omio's users. If you are prioritising price take the coach with prices starting from £27. For those with little time consider booking a flight which can get you there in 1h 25m. The ticket price range depends on the travel mode: a coach costs an average of £27, and a train costs an average of £81.

Distance: 580 km

Compare bus with

Most popular
Coach
Flight
Train

£57

Average Price

Cheapest

£73

Average Price

£94

Average Price

12h 26m

Average total duration

11h 56m

Onboard

+

30m

Additional time*

4h 25m

Average total duration

Fastest

1h 25m

Onboard

+

3h 0m

Additional time*

11h 48m

Average total duration

11h 18m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Siena to Lyon bus times

The table below shows live departures for Siena to Lyon coaches for today, Thursday 16 April. You can also manually refresh the results below to see updated coach journeys.

Last updated at
ProviderDepartsDurationArrivesChanges
Tickets
meinfernbus_flixbusFlixBus · FlixBus4:10 Siena, Stazione FS (Piazzale Carlo Rosselli)
15h00
19:10 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1 change
meinfernbus_flixbusFlixBus8:40 Siena, Stazione FS (Piazzale Carlo Rosselli)
12h00
20:40 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)0 changesdirect
itab2126 · 30928:55 Siena, Stazione FS (Piazzale Carlo Rosselli)
13h30
22:25 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1 change
meinfernbus_flixbusFlixBus · FlixBus12:51 Siena, Siena/Viale Pietro Toselli
15h39
4:30 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1 change
meinfernbus_flixbusFlixBus · FlixBus14:05 Siena, Stazione FS (Piazzale Carlo Rosselli)
14h25
4:30 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1 change
itab3811 · 389815:55 Siena, Stazione FS (Piazzale Carlo Rosselli)
19h00
10:55 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1 change
meinfernbus_flixbusFlixBus · FlixBus16:10 Siena, Stazione FS (Piazzale Carlo Rosselli)
14h35
6:45 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1 change
meinfernbus_flixbusFlixBus · FlixBus · FlixBus18:25 Siena, Stazione FS (Piazzale Carlo Rosselli)
15h35
10:00 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)2 changes
meinfernbus_flixbusFlixBus · FlixBus22:45 Siena, Stazione FS (Piazzale Carlo Rosselli)
13h25
12:10 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1 change

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Siena to Lyon by train, coach or flight

Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
17 Apr
Sat
18 Apr
Sun
19 Apr
Mon
20 Apr
Tue
21 Apr
Wed
22 Apr
Thu
23 Apr

Why should you book Siena to Lyon coaches with Omio?

FlixBus as well as Curcio Viaggi or Itabus offer coaches services from Siena to Lyon.
Omio is an official ticket reseller for all your travel options from Siena to Lyon.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Curcio Viaggi or Itabus to find the best option for your trip from Siena to Lyon.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Siena to Lyon.

Why book with Omio over Wanderu, Trainline or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Curcio Viaggi or Itabus to find the best option for your trip from Siena to Lyon.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Siena to Lyon.

Journey information

Overview: Bus from Siena to Lyon

ItalyItaly
FranceFrance
Icon of bus

Buses from Siena to Lyon run on average 8 times per day, taking around 11h 56m. Cheap bus tickets for this journey start at £27 if you book in advance.

There are 1 coaches per day. The earliest coach runs at 00:05, the last at 23:30. The fastest coach covers the 580 km distance in 12h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
580 km
Average bus duration
11h 56m
Cheapest ticket price
£27
Buses per day
8
Direct buses
1
Fastest bus
12h 0m
First bus
0:05
Last bus
23:30
Cheapest Month
Mar
Cheapest Day
Thu
High Season
Oct - Dec
Low Season
Jan - Mar
Busiest Day
Sun
Least Busy Day
Wed
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Curcio Viaggi, Itabus from Siena to LyonYou can travel by bus between Siena to Lyon with FlixBus, Curcio Viaggi, Itabus for as low as £27. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
12h 0m
Cheapest Price
£42
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
13h 50m
Cheapest Price
£56
Itabus frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

Curcio Viaggi

Luggage & cancellation policy
Average Duration
14h 15m
Cheapest Price
£51
Curcio Viaggi frequency
1 a day

FAQs: Siena to Lyon coach

Find answers to the most common questions about traveling from Siena to Lyon by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Siena to Lyon can start from as little as £27 when you book in advance. The average coach ticket price for Siena to Lyon is £57; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Siena to Lyon is 12h 0m to travel the 580 km long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Siena to Lyon leaves at 0:05. Plan your trip with the Journey Planner from Omio.
The latest coach from Siena to Lyon leaves at 23:30.
Yes, there are 1 direct coaches a day from Siena to Lyon with FlixBus. Schedules can vary on holidays or weekends with fewer direct coaches.
When taking a coach from Siena to Lyon, you can count on FlixBus, Curcio Viaggi, Itabus for the best way to get you to Lyon. You can also check all possible coach companies who offer a service between Siena and Lyon and compare the amenities they offer before buying a coach ticket.
A trip to Lyon from Siena is worth doing but not as a day trip with a journey time of 12h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Siena to Lyon is March.
It's helpful to compare your options as there are 3 ways to travel between Siena and Lyon including taking a train, coach and flight.
Yes, the following accessibility options are available when taking the coach from Siena to Lyon:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, there are bathrooms on board the coach from Siena to Lyon for coach company FlixBus, Itabus.
Whether you can cancel your coach ticket from Siena to Lyon depends on the coach companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the coach with coach company FlixBus, Itabus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Siena to Lyon.
Yes, the following luggage options are included when booking a coach ticket from Siena to Lyon:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
  • Itabus
    • One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a coach ticket from Siena to Lyon:
  • FlixBus
    • Additional luggage can be purchased for a fee.
  • Itabus
    • 5€ per additional bag.
Yes, you can bring your pet on the coach from Siena to Lyon. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
  • Itabus
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
You can reserve your seat on the coach from Siena to Lyon with the following coach company: FlixBus, Itabus
Yes, there are USB plugs on board the coach from Siena to Lyon with the following coach company: FlixBus, Itabus.
Yes, there is Wifi on board the coach from Siena to Lyon with the following coach company: FlixBus, Itabus.

popular bus stations

Important Stations and Airports in Siena and Lyon

Siena
Lyon
The major coach station for departures in Siena is Siena, Stazione FS (Piazzale Carlo Rosselli). Find all the information you need to know about services, amenities and connections at Siena, Stazione FS (Piazzale Carlo Rosselli) for your trip from Siena to Lyon.
Siena, Stazione FS (Piazzale Carlo Rosselli)
information
Siena, Siena/Viale Pietro Toselli
information

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