The cheapest and fastest coaches from Lyon to Siena
Cheapest price
£44
Average price
£58
Fastest journey
11 h 20 m
Average duration
13 h 20 m
Buses per day
6
Distance
580 km
The best way to find a cheap coach ticket from Lyon to Siena is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Lyon to Siena will cost around £58 if you buy it on the day, but you can find cheap coach tickets today for only £44.
Of the 6 buses that leave Lyon for Siena every day 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 580 km distance in an average of 13 h 20 m but if you time it right, some buses will get you there in just 11 h 20 m .
The slowest buses will take 15 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus9:3511h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)20:55Siena, Stazione FS (Piazzale Carlo Rosselli)£441One-way0 changes
FlixBus23:0012h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)11:20Siena, Stazione FS (Piazzale Carlo Rosselli)£451One-way0 changes
FlixBus · FlixBus3:1515h00Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)18:15Siena, Stazione FS (Piazzale Carlo Rosselli)£531One-way1 change
FlixBus · FlixBus14:5514h35Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)5:30Siena, Stazione FS (Piazzale Carlo Rosselli)£611One-way1 change
FlixBus · FlixBus1:1513h25Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)14:40Siena, Stazione FS (Piazzale Carlo Rosselli)£631One-way1 change
FlixBus9:3511h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)20:55Siena, Stazione FS (Piazzale Carlo Rosselli)£441One-way0 changes
FlixBus23:0012h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)11:20Siena, Stazione FS (Piazzale Carlo Rosselli)£451One-way0 changes
FlixBus · FlixBus1:1513h25Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)14:40Siena, Stazione FS (Piazzale Carlo Rosselli)£631One-way1 change
FlixBus · FlixBus14:5514h35Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)5:30Siena, Stazione FS (Piazzale Carlo Rosselli)£611One-way1 change
FlixBus · FlixBus3:1515h00Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)18:15Siena, Stazione FS (Piazzale Carlo Rosselli)£531One-way1 change
Live departures
Lyon to Siena bus times
The table below shows live departures for Lyon to Siena coaches for tomorrow, Saturday 6 June. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 1:15 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 13h25 | 14:40 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
FlixBus · FlixBus | 3:15 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 15h00 | 18:15 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
FlixBus | 9:35 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 11h20 | 20:55 Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 changesdirect | |
FlixBus · FlixBus | 14:55 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 14h35 | 5:30 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
3897 · 2126 | 15:30 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h20 | 10:50 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
FlixBus | 23:00 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 12h20 | 11:20 Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 changesdirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Siena by coach
Compare coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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12 Jun
Why should you book Lyon to Siena coaches with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Lyon to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Lyon to Siena.
Journey information
Overview: Bus from Lyon to Siena
Buses from Lyon to Siena run on average 7 times per day, taking around 15h 8m. Cheap bus tickets for this journey start at £29 if you book in advance.
There are 1 coaches per day. The earliest coach runs at 00:25, the last at 23:00. The fastest coach covers the 580 km distance in 13h 30m.
Distance 580 km |
Average bus duration 15h 8m |
Cheapest ticket price £29 |
Buses per day 7 |
Direct buses 1 |
Fastest bus 13h 30m |
First bus 0:25 |
Last bus 23:00 |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Mon |
Best time to book 28 days |
Bus providers: FlixBus, Itabus from Lyon to SienaYou can travel by bus between Lyon to Siena with FlixBus, Itabus for as low as £29. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
FAQs: Lyon to Siena coach
Find answers to the most common questions about traveling from Lyon to Siena by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Important Stations and Airports in Lyon and Siena
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Most popular bus connections from Lyon
More options for your journey from Lyon to Siena
Here are some other resources that might have the information you need

