- Must visit
Galleria degli Uffizi
Major art museum displaying Botticelli, Leonardo and Michelangelo, essential for understanding Florentine Renaissance painting.
Omio recommends booking the coach as it is the most popular option from Nyon to Florence among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £63 For those with little time, consider booking a flight, which has an average total journey time of 4h 55m. Average ticket prices depend on the travel mode: a coach costs an average of £63, while a flight costs an average of £372.
Distance: 489 km
Most popular Coach | Flight | Train | Driving |
|---|---|---|---|
£63 Average Price Cheapest | £372 Average Price | £290 Average Price | £105 Average Price (fuel + tolls) |
13h 51m Average total duration 13h 21m Onboard + 30m Additional time* | 4h 55m Average total duration Fastest 2h 55m Onboard + 2h 0m Additional time* | 7h 28m Average total duration 6h 58m Onboard + 30m Additional time* | 7h 8m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Nyon to Florence:
A coach is £227 less than a train for this route with tickets for a train from Nyon to Florence costing on average £290.
A coach is £310 less than a flight for this route with tickets for a flight from Nyon to Florence costing on average £372.
Other travel options to Florence take longer:
Train takes on average 6h 58m.
Coach takes on average 13h 21m.
Tickets start at around £63 compared to roughly £105 in fuel and tolls — a saving of about £42. The journey takes 13h 21m versus 7h 8m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
The table below shows live departures for Nyon to Florence coaches for today, Friday 18 September. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 19:35 Nyon | 11h45 | 7:20 Florence | 0 changesdirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Nyon to Florence run on average 4 times per day, taking around 13h 21m. Cheap bus tickets for this journey start at £54 if you book in advance.
The earliest coach runs at 02:20, the last at 23:25. The fastest coach covers the 489 km distance in 12h 30m.
Distance 489 km |
Average bus duration 13h 21m |
Cheapest ticket price £54 |
Buses per day 4 |
Fastest bus 12h 30m |
First bus 2:20 |
Last bus 23:25 |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 35 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
Major art museum displaying Botticelli, Leonardo and Michelangelo, essential for understanding Florentine Renaissance painting.
Museum housing Michelangelo’s David alongside unfinished sculptures and Florentine paintings in a compact, focused setting.
Vast former Medici residence with lavish rooms, court art and a panoramic garden-facing setting across the Arno.
Grand civic square surrounded by historic buildings and open-air sculpture, ideal for architecture, people-watching and evening walks.
Lively square beside the cathedral, central for orienting yourself and admiring the baptistery, facade details and constant street life.
Classic terrace viewpoint with sweeping views over Florence, especially rewarding at sunset and easy to combine with uphill walks.
Thick Tuscan bread soup with tomatoes, olive oil and basil. A frugal Florentine classic that celebrates stale unsalted bread and summer produce.
Hearty soup of black kale, cannellini beans, vegetables and stale Tuscan bread. A traditional peasant dish closely linked with Florence and Tuscany.
Large T-bone steak from Chianina beef, grilled rare over coals. It is Florence’s signature meat dish and prized for its simplicity and quality.
Long-standing sandwich shop near the market, popular for schiacciata filled with Tuscan salumi and cheeses. Informal and very Florentine.
Lively traditional trattoria known for hearty Tuscan dishes such as ribollita and Florentine steak in a classic, bustling setting.
Historic market stall famed for lampredotto sandwiches. Casual, quick and deeply traditional, ideal for trying authentic Florentine street food.
Florence is pricier than many Italian cities, with central stays, museum-area dining and tourist services pushing up daily costs, though local cafés and buses remain fairly manageable.
Tipping is not obligatory. In restaurants, round up or leave 5-10% for good service if no service charge applies. Taxis are usually rounded up. In cafés, small change is enough.
Official public transport app
Santa Maria Novella -> Firenze Santa Maria Novella
Find answers to the most common questions about traveling from Nyon to Florence by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

Most Nyon to Florence buses use the Genève, Aéroport to Scandicci, Villa Costanza (Firenze) station pair, with some services arriving at Firenze, Piazzale Montelungo. Use this guide to compare Nyon and Florence bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Scandicci, Villa Costanza (Firenze) is 1 km from Florence city centre. Public transport options include:
Scandicci, Villa Costanza (Firenze) has practical services for this route, including Wifi, Parking, ATM, Accessibility, WC and Ticket Office.
Free Wi-Fi. ATMs are located near the entrance.
Ticket office support is available at Scandicci, Villa Costanza (Firenze).
Available at Scandicci, Villa Costanza (Firenze): Parking, WC.
Accessibility facilities are available at Scandicci, Villa Costanza (Firenze): Elevators, ramps.
Firenze, Piazzale Montelungo is 1 km from Florence city centre. Public transport options include:
Firenze, Piazzale Montelungo has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC and Ticket Office.
Free Wi-Fi. ATMs are located near the entrance.
Ticket office support is available at Firenze, Piazzale Montelungo.
Available at Firenze, Piazzale Montelungo: Parking, Taxis, WC.
Accessibility facilities are available at Firenze, Piazzale Montelungo: Elevators, ramps.
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