- Must visit
Städel Museum
Major art museum on the Museumsufer with European masterpieces from the Middle Ages to modern art in a substantial permanent collection.
Cheapest price on 07 Oct
£28
Average ticket price on 07 Oct
£41
Fastest journey on 07 Oct
10 h 5 m
Average journey duration on 07 Oct
11 h 20 m
Buses on 07 Oct
8
Distance
563 km
The best way to find a cheap coach ticket from Lyon to Frankfurt am Main is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Lyon to Frankfurt am Main will cost around £41 if you buy it on the day, but you can find cheap coach tickets today for only £28.
On Wed 07 Oct, we found 8 buses from Lyon to Frankfurt am Main, including 4 direct services.
These direct buses cover the 563 km distance in an average of 11 h 20 m but if you time it right, some buses will get you there in just 10 h 5 m .
The slowest buses will take 12 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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FlixBus · FlixBusBuses from Lyon to Frankfurt am Main run on average 10 times per day, taking around 11h 23m. Cheap bus tickets for this journey start at £21 but you can travel from only £20 by train.
There are 5 coaches per day. The earliest coach runs at 00:15, the last at 23:41. The fastest coach covers the 563 km distance in 10h 0m.
Distance 563 km |
Average bus duration 11h 23m |
Cheapest ticket price £21 |
Buses per day 10 |
Direct buses 5 |
Fastest bus 10h 0m |
First bus 0:15 |
Last bus 23:41 |
Cheapest Month Sept |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Mon |
Best time to book 42 days |
The table below shows live departures for Lyon to Frankfurt am Main coaches for today, Tuesday 6 October. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
51511 | 3:20 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h50 | 14:10 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 changesdirect | |
FlixBus+ FlixTrain | 5:20 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h35 | 15:55 Frankfurt South station | 1 change | |
FlixBus | 7:30 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 12h45 | 20:15 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 changesdirect | |
FlixBus · FlixBus | 18:05 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 12h15 | 6:20 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 change | |
FlixBus · FlixBus | 18:05 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 11h55 | 6:00 Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 change | |
FlixBus | 23:00 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 11h20 | 10:20 Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 changesdirect | |
FlixBus | 23:00 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 11h45 | 10:45 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 changesdirect | |
| Wednesday 7 October | |||||
FlixBus | 2:20 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h05 | 12:25 Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 changesdirect | |
FlixBus | 2:20 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h30 | 12:50 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 changesdirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
Major art museum on the Museumsufer with European masterpieces from the Middle Ages to modern art in a substantial permanent collection.
Extensive natural history museum with dinosaur skeletons, fossils and scientific exhibits, especially popular for families and rainy days.
Museum of modern and contemporary art known for its striking triangular building and rotating exhibitions near the old town.
Recreated old town quarter between Römer and the cathedral, with narrow lanes, traditional-style facades and small public squares for strolling.
Frankfurt’s central historic square, framed by timbered buildings and used for markets, events and some of the city’s best-known views.
Riverside museum district with promenades, major collections and broad Main views, ideal for a scenic walk between cultural stops.
A tart, slightly sparkling apple wine served in a ribbed glass. It is Frankfurt’s signature drink and a staple in traditional cider taverns.
Green herb sauce made with seven fresh herbs, traditionally served with boiled eggs and potatoes. It is one of Frankfurt’s best-known regional specialities.
Pork sausages, usually lightly smoked, served hot with bread, potato salad or sauerkraut. They are a classic everyday dish in Frankfurt and Hesse.
Casual market hall stand famous for Frankfurter sausages and quick local bites in the lively Kleinmarkthalle.
Traditional Apfelwein tavern in Sachsenhausen, known for Green Sauce, sausages and a lively local atmosphere.
Historic cider house serving classic Frankfurt dishes and apple wine in a busy, wood-panelled setting popular with locals and visitors.
Moderate for Germany: hotels and dining cost more than smaller cities, but public transport is efficient and many everyday meals remain reasonably priced.
Service is not usually included. Round up or tip about 5-10% in restaurants, round up taxi fares, and leave small change in cafés.
Official public transport app
Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) -> Frankfurt (Main) Hauptwache
The most popular day trips by bus from Frankfurt am Main are Cologne, Heidelberg, Mainz, Wiesbaden and Mannheim. Find out what you can do in these day trip destinations and how to book your bus from Frankfurt am Main on Omio.

Cologne is known for its towering cathedral, Roman heritage and relaxed Rhineland spirit. Museums, riverfront views and a strong brewing culture give the city an open, sociable feel.
There are 25 coaches per day. The earliest coach runs at 00:05, the last at 23:55. The fastest coach covers the 153 km distance in 1h 15m.

Heidelberg is a historic university city on the River Neckar, known for its baroque Altstadt and Heidelberg Castle. A large student population keeps the city lively, while riverside views and the Philosophenweg reflect its Romantic past.
There are 23 coaches per day. The earliest coach runs at 00:04, the last at 23:25. The fastest coach covers the 79 km distance in 1h 5m.

Mainz on the Rhine is known for its Roman past, Gutenberg heritage and relaxed wine culture. Its old town, cathedral and riverside give the state capital a lively but easy-going feel.
There are 2 coaches per day. The earliest coach runs at 00:15, the last at 23:55. The fastest coach covers the 32 km distance in 35m.

Wiesbaden is known for its thermal springs, stately architecture and refined spa-town character. Set near the Rhine, it blends leafy parks, elegant squares and a calm, affluent atmosphere.
The earliest coach runs at 00:15, the last at 23:55.

Mannheim is known for its grid-plan centre, industrial heritage and confident cultural life. The Baroque palace, the Wasserturm and a strong music scene give the city a practical yet distinctive character.
There are 25 coaches per day. The earliest coach runs at 00:04, the last at 23:40. The fastest coach covers the 70 km distance in 50m.
Find answers to the most common questions about traveling from Lyon to Frankfurt am Main by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

Most Lyon to Frankfurt am Main buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) station pair, with some services arriving at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36). Use this guide to compare Lyon and Frankfurt am Main bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, Gare Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: Café de la Gare (in the station), Bistro Lyonnais (0.2 km), Fast Food Express (0.3 km).
Free Wi-Fi. ATMs are located near the main entrance and in the shopping area.
Ticket office support is available at Lyon, Gare Perrache.
Available at Lyon, Gare Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Perrache: Elevators, ramps.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
Frankfurt am Main, Mannheimer Straße (Hauptbahnhof) is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Mannheimer Straße (Hauptbahnhof) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower and Ticket Office.
Food options include: Several restaurants nearby.
Wi-Fi is available at Frankfurt am Main, Mannheimer Straße (Hauptbahnhof). ATMs are aTMs available within the station vicinity.
Ticket office support is available at Frankfurt am Main, Mannheimer Straße (Hauptbahnhof).
Available at Frankfurt am Main, Mannheimer Straße (Hauptbahnhof): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Mannheimer Straße (Hauptbahnhof): Wheelchair accessible with ramps available.
Here are some other resources that might have the information you need