How to get to Brussels from Siena

Fri 23 Oct
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Travel Information

Compare coach and flight for Siena to Brussels

Omio recommends booking the coach as it is the most popular option from Siena to Brussels among Omio's users. If you are prioritising price, take the flight, with an average ticket price of £61 For those with little time, consider booking a flight, which has an average total journey time of 3h 46m. Average ticket prices depend on the travel mode: a flight costs an average of £61, while a coach costs an average of £86.

Distance: 989 km

Compare bus with

Most popular
Coach
Flight
Driving

£86

Average Price

£61

Average Price

Cheapest

£17

Average Price

(fuel + tolls)

23h 14m

Average total duration

22h 44m

Onboard

+

30m

Additional time*

3h 46m

Average total duration

Fastest

1h 46m

Onboard

+

2h 0m

Additional time*

13h 23m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

Malta Air

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Compare ways to travel from Siena to Brussels

Compare the available ways to get from Siena to Brussels, with the key details around price, speed, convenience, and direct service.

The cheapest way to travel from Siena to Brussels is a flight with an average price of £61.

This is compared to other travel options from Siena to Brussels:

A flight is £25 less than a coach for this route with tickets for a coach from Siena to Brussels costing on average £86.

The fastest way to travel from Siena to Brussels is by flight with an average journey time of 3h 46m.

Other travel options to Brussels take longer:

Coach takes on average 23h 14m.

It's helpful to compare your options as there are 2 ways to travel between Siena and Brussels including taking a coach and flight.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around £86 compared to roughly £17 in fuel and tolls — a saving of about -£68. The journey takes 22h 44m versus 13h 23m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Travel options
from Siena to Brussels

How to get to Brussels from Siena by train, bus, flight or ferry.

Our recommendation

flight

The best way to travel from Siena to Brussels is by taking a flight because it’s the best combination of price and speed.

  • RyanairFR 3747
    21:001h45
    Pisa International Airport
    22:45Brussels South Charleroi Airport
    £401One-way
    0 changes

Cheapest

  • RyanairFR 3747
    21:001h45
    Pisa International Airport
    22:45Brussels South Charleroi Airport
    £401One-way
    0 changes

Fastest

  • RyanairFR 3747
    21:001h45
    Pisa International Airport
    22:45Brussels South Charleroi Airport
    £401One-way
    0 changes

Other options

  • FlixBusFlixBus · FlixBus · FlixBus
    10:4025h40
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    12:20Brussels, Brussels South (Gare du Midi)
    £871One-way
    2 changes
  • FlixBusFlixBus · FlixBus · FlixBus
    15:0526h50
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    17:55Brussels, Brussels South (Gare du Midi)
    £881One-way
    2 changes
  • FlixBusFlixBus · FlixBus · FlixBus
    14:5127h04
    Siena, Siena/Viale Pietro Toselli
    17:55Brussels, Brussels South (Gare du Midi)
    £881One-way
    2 changes
  • FlixBusFlixBus+easyJetU22982
    7:0013h20
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    20:20Brussels Airport
    £1541One-way
    1 change
  • FlixBusFlixBus+easyJetU22982
    10:459h35
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    20:20Brussels Airport
    £1561One-way
    1 change
  • FlixBusFlixBus+CitizenPlane2982
    7:0013h20
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    20:20Brussels Airport
    £1771One-way
    1 change

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, coaches, flights and ferries

Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
23 Oct
Sat
24 Oct
Sun
25 Oct
Mon
26 Oct
Tue
27 Oct
Wed
28 Oct
Thu
29 Oct

Best day trips from Brussels by train

The most popular day trips by train from Brussels are Bruges, Ghent, Antwerp, Leuven and Liège. Find out what you can do in these day trip destinations and how to book your train from Brussels on Omio.

A view of Ghent

Day trip from Brussels to Ghent by train

Why visit Ghent for the day?

Ghent is known for its canals, medieval centre and lively student atmosphere. Historic quays, Gravensteen and Saint Bavo's Cathedral give the city a cultured yet relaxed character.

A view of Antwerp

Day trip from Brussels to Antwerp by train

Why visit Antwerp for the day?

Antwerp is known for diamonds, fashion and the baroque legacy of Rubens. Its compact centre pairs grand guild houses and lively squares with a creative, modern waterfront.

A view of Leuven

Day trip from Brussels to Leuven by train

Why visit Leuven for the day?

Leuven is known for its historic university, brewing heritage and energetic student life. Its Gothic centre, led by the Grote Markt and Town Hall, feels grand yet easy-going.

A view of Liège

Day trip from Brussels to Liège by train

Why visit Liège for the day?

Liège is a lively Walloon city on the Meuse, known for its industrial heritage and strong food culture. Historic streets, busy markets and the Montagne de Bueren give it an energetic, down-to-earth character.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Siena to Brussels

Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Siena to Brussels.

FAQs
There are 2 options to travel between Siena and Brussels including taking a coach and flight.
The cheapest way to travel from Siena to Brussels is a flight with an average price of £61.

This is compared to other travel options from Siena to Brussels:

A flight is £25 less than a coach for this route with tickets for a coach from Siena to Brussels costing on average £86.

The fastest way to travel from Siena to Brussels is by flight with an average journey time of 3h 46m.

Other travel options to Brussels take longer:

Coach takes on average 23h 14m.

The Siena to Brussels distance is approximately 989 km.
The average frequency per day from Siena to Brussels is:
  • Around 5 coaches per day.
  • Around 2 flights per day.

However, we recommend checking specific travel dates for your route between Siena and Brussels as scheduled services by coach and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Siena to Brussels:
  • Flights mostly depart from Pisa International Airport and arrive in Brussels South Charleroi Airport.
  • Coaches mostly depart from Siena, Stazione FS (Piazzale Carlo Rosselli) and arrive in Brussels, Brussels South (Gare du Midi).
If finding a good deal is your main consideration for your trip from Siena to Brussels, then we'll help you find the best value travel companies for you:
  • Travel with Malta Air, Ryanair to go to Brussels by flight.
  • Travel with FlixBus to go to Brussels by coach.
Yes, there is a direct route available from Siena to Brussels:
  • 2 direct flights per day with Malta Air, Ryanair.
Omio customers who travel from Siena to Brussels often also extend their vacation to go to Paris, Amsterdam, Bruges, London, Luxembourg. Omio can help you plan your trip by finding the best connections between Brussels and these popular destinations at a great price.
To get from Siena to Brussels, you can choose from several travel options including coach and flight.
Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art. Enjoy a leisurely stroll through Parc du Cinquantenaire, home to impressive arches and museums. Sample Belgian chocolates at renowned chocolatiers, and discover the lively atmosphere of the Saint-Géry district with trendy bars and cafes. Attend a performance at the historic La Monnaie opera house. Visit Grand Place, a UNESCO World Heritage site, the Atomium for panoramic city views, the famous Manneken Pis statue, the Royal Palace of Brussels, and the Magritte Museum for surrealist art.
To explore Brussels' main attractions, including the Grand Place, Atomium, and various museums, a stay of 2 to 3 days is generally sufficient.

Travelling from Siena to Brussels: related information

Here are some other resources that might have the information you need

HomeTravelTravel to BelgiumTravel to BrusselsHow to get to Brussels from Siena

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