4.9
4.6
Omio recommends booking the train as it is the most popular option from Prague to Mainz among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £39 For those with little time, consider booking a flight, which has an average total journey time of 4h 52m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a coach costs an average of £39, while a flight costs an average of £268.
Distance: 439 km
Most popular Train | Coach | Flight | Driving |
|---|---|---|---|
£105 Average Price | £39 Average Price Cheapest | £268 Average Price | £86 Average Price (fuel + tolls) |
8h 8m Average total duration 7h 38m Onboard + 30m Additional time* | 9h 28m Average total duration 8h 58m Onboard + 30m Additional time* | 4h 52m Average total duration Fastest 2h 52m Onboard + 2h 0m Additional time* | 5h 11m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare the available ways to get from Prague to Mainz, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Prague to Mainz:
A coach is £66 less than a train for this route with tickets for a train from Prague to Mainz costing on average £105.
A coach is £230 less than a flight for this route with tickets for a flight from Prague to Mainz costing on average £268.
Other travel options to Mainz take longer:
Train takes on average 8h 8m.
Coach takes on average 9h 28m.
Tickets start at around £105 compared to roughly £86 in fuel and tolls — a saving of about -£18. The journey takes 7h 38m versus 5h 11m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
How to get to Mainz from Prague by train, bus, flight or ferry.
The best way to travel from Prague to Mainz is by taking a coach because it’s the best combination of price and speed.
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Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
The most popular day trips by train from Mainz are Frankfurt am Main, Rüdesheim am Rhein, Wiesbaden, Sankt Goar and Cologne. Find out what you can do in these day trip destinations and how to book your train from Mainz on Omio.
Frankfurt am Main pairs Germany’s best-known skyline with a rebuilt old town and a broad stretch of museums along the Main. Known as a financial hub and trade fair city, it also has apple wine taverns and a distinctly international feel.
Rüdesheim am Rhein is known for Riesling, vineyard-covered hills and a lively old town on the Rhine. The Drosselgasse and the Niederwald Monument give it a distinctly traditional, riverfront character.
Wiesbaden is known for its thermal springs, stately architecture and refined spa-town character. Set near the Rhine, it blends leafy parks, elegant squares and a calm, affluent atmosphere.
Cologne is known for its towering cathedral, Roman heritage and relaxed Rhineland spirit. Museums, riverfront views and a strong brewing culture give the city an open, sociable feel.
Travel to Mainz easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Mainz.
This is compared to other travel options from Prague to Mainz:
A coach is £66 less than a train for this route with tickets for a train from Prague to Mainz costing on average £105.
A coach is £230 less than a flight for this route with tickets for a flight from Prague to Mainz costing on average £268.
Other travel options to Mainz take longer:
Train takes on average 8h 8m.
Coach takes on average 9h 28m.
However, we recommend checking specific travel dates for your route between Prague and Mainz as scheduled services by train, coach and flight can vary by season or day of the week.
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