Travel Information
Compare train, coach and flight for Prague to Mainz
Omio recommends booking the flight as it is the most popular option from Prague to Mainz among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £41 For those with little time, consider booking a flight, which has an average total journey time of 4h 42m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a coach costs an average of £41, while a flight costs an average of £272.
Distance: 439 km
Compare flight with
Most popular Flight | Train | Coach |
|---|---|---|
£272 Average Price | £106 Average Price | £41 Average Price Cheapest |
4h 42m Average total duration Fastest 2h 42m Onboard + 2h 0m Additional time* | 8h 5m Average total duration 7h 35m Onboard + 30m Additional time* | 9h 31m Average total duration 9h 1m Onboard + 30m Additional time* |
1.3 - 2.6kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Mainz
How to get to Mainz from Prague by train, bus, flight or ferry.
Our recommendation
The best way to travel from Prague to Mainz is by taking a coach because it’s the best combination of price and speed.
(Prague -> Amsterdam)23:006h55Praha, ÚAN Florenc5:55Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)£231One-way0 changes
Cheapest
(Prague -> Amsterdam)23:006h55Praha, ÚAN Florenc5:55Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)£231One-way0 changes
Fastest
DE441012:100h50Prague Vaclav Havel Airport13:00Frankfurt am Main Airport£2491One-way0 changes
Other options
EX 354 · 3578 · ICE 2213:358h43Prague hlavní nádraží22:18Mainz Hbf£491One-way2 changes
EX 354 · 3576 · ICE 526 · S813:358h20Prague hlavní nádraží21:55Mainz Hbf£601One-way3 changes
EX 358 · 3570 · ICE 269:358h43Prague hlavní nádraží18:18Mainz Hbf£601One-way2 changes
FlixBus3:408h20Praha, Na Knížecí12:00Mainz, Binger Schlag (Kurzzeitparkplatz)£301One-way0 changes
FlixBus3:258h35Prague, Central Train Station12:00Mainz, Binger Schlag (Kurzzeitparkplatz)£301One-way0 changes
FlixBus · FlixBus23:059h05Praha, ÚAN Florenc8:10Mainz, Binger Schlag (Kurzzeitparkplatz)£321One-way1 change
EW77312:301h15Prague Vaclav Havel Airport13:45Cologne Bonn Airport£661One-way0 changes
LH13939:101h10Prague Vaclav Havel Airport10:20Frankfurt am Main Airport£711One-way0 changes
LH139714:301h10Prague Vaclav Havel Airport15:40Frankfurt am Main Airport£711One-way0 changes
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
18 Sept
19 Sept
20 Sept
21 Sept
22 Sept
23 Sept
24 Sept
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Prague to Mainz
Travel to Mainz easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Mainz.

This is compared to other travel options from Prague to Mainz:
A coach is £41 less than a flight for this route with tickets for a flight from Prague to Mainz costing on average £83.
A coach is £65 less than a train for this route with tickets for a train from Prague to Mainz costing on average £106.
Other travel options to Mainz take longer:
Train takes on average 8h 5m.
Coach takes on average 9h 31m.
- Around 72 flights per day.
- Around 8 trains per day.
- Around 5 coaches per day.
However, we recommend checking specific travel dates for your route between Prague and Mainz as scheduled services by train, coach and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Mainz Hbf.
- Coaches mostly depart from Praha, Na Knížecí and arrive in Mainz, Binger Schlag (Kurzzeitparkplatz).
- Travel with Deutsche Bahn, České dráhy, ÖBB | Euro City (EC), České dráhy (ČD), ÖBB | Railjet to go to Mainz by train.
- Travel with FlixBus, BlaBlaCar to go to Mainz by coach.
- Travel with Lufthansa, Air Dolomiti, Condor Flugdienst to go to Mainz by flight.
- 2 direct coaches per day with FlixBus, BlaBlaCar.
- 9 direct flights per day with Air Dolomiti.
Travelling from Prague to Mainz: related information
Here are some other resources that might have the information you need
