Travel Information
Compare train, coach and flight for Mainz to Lyon
Omio recommends booking the flight as it is the most popular option from Mainz to Lyon among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £48 For those with little time, consider booking a flight, which has an average total journey time of 3h 18m. If you are seeking to minimise your carbon footprint, the coach is your best option, with estimated CO2 emissions of 0.5 - 1.3kg. Average ticket prices depend on the travel mode: a coach costs an average of £48, while a flight costs an average of £187.
Distance: 536 km
Compare flight with
Most popular Flight | Coach |
|---|---|
£187 Average Price | £48 Average Price Cheapest |
3h 18m Average total duration Fastest 1h 18m Onboard + 2h 0m Additional time* | 10h 40m Average total duration 10h 10m Onboard + 30m Additional time* |
1.6 - 3.2kg CO2 emissions | 0.5 - 1.3kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Mainz to Lyon
How to get to Lyon from Mainz by train, bus, flight or ferry.
Our recommendation
The best way to travel from Mainz to Lyon is by taking a coach because it’s the best combination of price and speed.
6:2015h30Mainz21:50Lyon£361One-way0 changes
Cheapest
6:2015h30Mainz21:50Lyon£361One-way0 changes
Fastest
6:2015h30Mainz21:50Lyon£361One-way0 changes
Other options
21:4016h05Mainz13:45Lyon£401One-way0 changes
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
08 Sept
09 Sept
10 Sept
11 Sept
12 Sept
13 Sept
14 Sept
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Mainz to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Lyon.

This is compared to other travel options from Mainz to Lyon:
A coach is £139 less than a flight for this route with tickets for a flight from Mainz to Lyon costing on average £187.
Other travel options to Lyon take longer:
Train takes on average 6h 32m.
Coach takes on average 10h 40m.
- Around 22 flights per day.
- Around 4 coaches per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Mainz and Lyon as scheduled services by train, coach and flight can vary by season or day of the week.
- Coaches mostly depart from Mainz, Binger Schlag (Kurzzeitparkplatz) and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Mannheim Hbf and arrive in Lyon Part Dieu.
- Travel with FlixBus, ORN Omnibusverkehr Rhein-Nahe GmbH to go to Lyon by coach.
- Travel with TGV, SNCF | TGV INOUI, vlexx to go to Lyon by train.
- Travel with Lufthansa to go to Lyon by flight.
- 1 direct trains per day with SNCF | TGV INOUI.
- 4 direct flights per day with Lufthansa.
Travelling from Mainz to Lyon: related information
Here are some other resources that might have the information you need

