4.9
4.6
Omio recommends booking the coach as it is the most popular option from Madrid to Setúbal among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £43 For those with little time, consider booking a flight, which has an average total journey time of 5h 32m. If you are seeking to minimise your carbon footprint, the coach is your best option, with estimated CO2 emissions of 0.5 - 1.2kg. Average ticket prices depend on the travel mode: a coach costs an average of £43, while a flight costs an average of £381.
Distance: 492 km
Most popular Coach | Flight | Driving |
|---|---|---|
£43 Average Price Cheapest | £381 Average Price | £86 Average Price (fuel + tolls) |
10h 39m Average total duration 10h 9m Onboard + 30m Additional time* | 5h 32m Average total duration Fastest 3h 32m Onboard + 2h 0m Additional time* | 5h 34m Average total duration (door-to-door) |
0.5 - 1.2kg CO2 emissions Lowest | 1.5 - 3.0kg CO2 emissions | - CO2 emissions |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare the available ways to get from Madrid to Setúbal, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Madrid to Setúbal:
A coach is £338 less than a flight for this route with tickets for a flight from Madrid to Setúbal costing on average £381.
Other travel options to Setúbal take longer:
Coach takes on average 10h 39m.
Tickets start at around £43 compared to roughly £86 in fuel and tolls — a saving of about £43. The journey takes 10h 9m versus 5h 34m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
How to get to Setúbal from Madrid by train, bus, flight or ferry.
The best way to travel from Madrid to Setúbal is by taking a flight because it’s the best combination of price and speed.
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Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
The most popular day trips by train from Setúbal are Lisbon, Palmela, Almada, Barreiro and Sesimbra. Find out what you can do in these day trip destinations and how to book your train from Setúbal on Omio.
Lisbon is Portugal’s hilly Atlantic capital, known for tiled streets, yellow trams and views from Alfama. Maritime history, fado and a lively café culture give the city a relaxed but distinctive character.
Almada sits across the Tagus from Lisbon and is best known for the Cristo Rei monument and views of the 25 de Abril Bridge. It mixes working-city character with riverfront spaces and easy access to the beaches of Costa da Caparica.
Travel to Setúbal easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Madrid to Setúbal.
This is compared to other travel options from Madrid to Setúbal:
A coach is £338 less than a flight for this route with tickets for a flight from Madrid to Setúbal costing on average £381.
Other travel options to Setúbal take longer:
Coach takes on average 10h 39m.
However, we recommend checking specific travel dates for your route between Madrid and Setúbal as scheduled services by coach and flight can vary by season or day of the week.
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