Travel optionsfrom Madrid to Santo Domingo
How to get to Santo Domingo from Madrid by train, bus, flight or ferry.
Our recommendation
The best way to travel from Madrid to Santo Domingo is by taking a flight because it’s the best combination of price and speed.
IB26316:059h20Madrid Barajas Airport19:25Santo Domingo£5481One-way0 changes
Cheapest
IB333+
IB456711:3014h15Madrid Barajas Airport19:45Santo Domingo£5391One-way1 change
Fastest
UX8916:108h40Madrid Barajas Airport18:50Santo Domingo£8191One-way0 changes
Other options
KL6127 · KL587714:3515h42Madrid Barajas Airport0:17Santo Domingo£13011One-way1 change
AF1401+
AF9084 · AF87896:2018h14Madrid Barajas Airport18:34Santo Domingo£13211One-way2 changes
KL1500+
KL6020 · KL73086:0018h34Madrid Barajas Airport18:34Santo Domingo£13211One-way2 changes
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Madrid to Santo Domingo
Travel to Santo Domingo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Madrid to Santo Domingo.

- Around 22 flights per day.
However, we recommend checking specific travel dates for your route between Madrid and Santo Domingo as scheduled services by flight can vary by season or day of the week.
- Flights mostly depart from Madrid Barajas Airport and arrive in Santo Domingo.
- Travel with Iberia, Air Europa, World2Fly, Delta Air Lines, American Airlines, Avianca to go to Santo Domingo by flight.
Travelling from Madrid to Santo Domingo: related information
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