Travel Information
Compare train, coach and flight for Frankfurt am Main to Plzeň
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Plzeň among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £27 For those with little time, consider booking a flight, which has an average total journey time of 3h 50m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a coach costs an average of £27, while a flight costs an average of £138.
Distance: 338 km
Compare train with
Most popular Train | Coach | Flight | Driving |
|---|---|---|---|
£55 Average Price | £27 Average Price Cheapest | £138 Average Price | £69 Average Price (fuel + tolls) |
5h 56m Average total duration 5h 26m Onboard + 30m Additional time* | 6h 24m Average total duration 5h 54m Onboard + 30m Additional time* | 3h 50m Average total duration Fastest 1h 50m Onboard + 2h 0m Additional time* | 4h 35m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.8kg CO2 emissions | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Plzeň:
A coach is £27 less than a train for this route with tickets for a train from Frankfurt am Main to Plzeň costing on average £65.
A coach is £295 less than a flight for this route with tickets for a flight from Frankfurt am Main to Plzeň costing on average £333.
Other travel options to Plzeň take longer:
Train takes on average 5h 58m.
Coach takes on average 7h 10m.
Tickets start at around £65 compared to roughly £69 in fuel and tolls — a saving of about £5. The journey takes 5h 28m versus 4h 35m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Frankfurt am Main to Plzeň
How to get to Plzeň from Frankfurt am Main by train, bus, flight or ferry.
Our recommendation
The best way to travel from Frankfurt am Main to Plzeň is by taking a coach because it’s the best combination of price and speed.
FlixBus · FlixBus22:008h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)6:00Plzeň, Centrální Autobusové Nádraží£251One-way1 change
Cheapest
FlixBus · FlixBus22:008h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)6:00Plzeň, Centrální Autobusové Nádraží£251One-way1 change
Fastest
DE441120:351h00Frankfurt am Main Airport21:35Prague Vaclav Havel Airport£1311One-way0 changes
Other options
ICE 27 · 3571+
36112:026h45Frankfurt Airport long-distance station18:47Plzen hl.n.£491One-way2 changes
ICE 629 · 3577+
36314:575h50Frankfurt (Main) Hbf20:47Plzen hl.n.£531One-way2 changes
ICE 629 · 3577+
36314:416h06Frankfurt Airport long-distance station20:47Plzen hl.n.£531One-way2 changes
FlixBus · FlixBus20:159h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)5:30Plzeň, Centrální Autobusové Nádraží£251One-way1 change
FlixBus11:156h25Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)17:40Plzeň, Centrální Autobusové Nádraží£261One-way0 changes
(Amsterdam -> Prague)22:304h55Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)3:25Plzeň, Centrální Autobusové Nádraží£271One-way0 changes
DE440715:001h00Frankfurt am Main Airport16:00Prague Vaclav Havel Airport£1411One-way0 changes
DE440910:001h00Frankfurt am Main Airport11:00Prague Vaclav Havel Airport£1521One-way0 changes
LO382 · LO52110:356h45Frankfurt am Main Airport17:20Prague Vaclav Havel Airport£1811One-way1 change
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Frankfurt am Main to Plzeň
Travel to Plzeň easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Plzeň.

This is compared to other travel options from Frankfurt am Main to Plzeň:
A coach is £28 less than a train for this route with tickets for a train from Frankfurt am Main to Plzeň costing on average £55.
A coach is £111 less than a flight for this route with tickets for a flight from Frankfurt am Main to Plzeň costing on average £138.
Other travel options to Plzeň take longer:
Train takes on average 5h 56m.
Coach takes on average 6h 24m.
- Around 47 flights per day.
- Around 13 trains per day.
- Around 8 coaches per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Plzeň as scheduled services by train, coach and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Plzen hl.n..
- Coaches mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Plzeň, Centrální Autobusové Nádraží.
- Travel with FlixBus to go to Plzeň by coach.
- Travel with Deutsche Bahn, Deutsche Bahn Intercity (DB IC) to go to Plzeň by train.
- Travel with KLM, Lufthansa to go to Plzeň by flight.
- 3 direct coaches per day with FlixBus.
Travelling from Frankfurt am Main to Plzeň: related information
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