Travel Information
Compare train, coach and flight for Frankfurt am Main to Brindisi
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Brindisi among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £90 For those with little time, consider booking a flight, which has an average total journey time of 4h 52m. Average ticket prices depend on the travel mode: a coach costs an average of £90, while a flight costs an average of £193.
Distance: 1277 km
Compare flight with
Most popular Flight | Coach | Driving |
|---|---|---|
£193 Average Price | £90 Average Price Cheapest | £355 Average Price (fuel + tolls) |
4h 52m Average total duration Fastest 2h 52m Onboard + 2h 0m Additional time* | 25h 3m Average total duration 24h 33m Onboard + 30m Additional time* | 16h 33m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frankfurt am Main to Brindisi:
A coach is £102 less than a flight for this route with tickets for a flight from Frankfurt am Main to Brindisi costing on average £193.
A coach is £270 less than a train for this route with tickets for a train from Frankfurt am Main to Brindisi costing on average £360.
Other travel options to Brindisi take longer:
Train takes on average 21h 47m.
Coach takes on average 25h 3m.
You'll arrive about 13h 41m sooner (2h 52m by flight vs 16h 33m by car) and save roughly £162 compared to fuel and tolls (£193 vs £355). You also avoid a long drive, giving you more time to relax or get on with your plans.
Driving is still worth considering if you want to stop along the way, are travelling with bulky luggage, or need a car at your destination.
Travel optionsfrom Frankfurt am Main to Brindisi
How to get to Brindisi from Frankfurt am Main by train, bus, flight or ferry.
Our recommendation
The best way to travel from Frankfurt am Main to Brindisi is by taking a coach because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus7:5026h15Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)10:05Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)£681One-way2 changes
Cheapest
FlixBus · FlixBus · FlixBus7:5026h15Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)10:05Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)£681One-way2 changes
Fastest
LH108+
LH690813:153h45Frankfurt am Main Airport17:00Brindisi Airport£2971One-way1 change
Other options
FlixBus · FlixBus · FlixBus13:4028h45Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)18:25Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)£821One-way2 changes
FlixBus · FlixBus · FlixBus1:0529h05Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)6:10Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)£851One-way2 changes
FlixBus · FlixBus · FlixBus16:0030h25Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)22:25Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)£851One-way2 changes
LX3603+
LX17229:454h15Frankfurt am Main Airport14:00Brindisi Airport£2491One-way1 change
LX1069 · LX17228:505h10Frankfurt am Main Airport14:00Brindisi Airport£2491One-way1 change
LX3605+
LX172413:006h30Frankfurt am Main Airport19:30Brindisi Airport£2491One-way1 change
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Frankfurt am Main to Brindisi
Travel to Brindisi easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Brindisi.

This is compared to other travel options from Frankfurt am Main to Brindisi:
A coach is £102 less than a flight for this route with tickets for a flight from Frankfurt am Main to Brindisi costing on average £193.
A coach is £270 less than a train for this route with tickets for a train from Frankfurt am Main to Brindisi costing on average £360.
Other travel options to Brindisi take longer:
Train takes on average 21h 47m.
Coach takes on average 25h 3m.
- Around 43 flights per day.
- Around 8 coaches per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Brindisi as scheduled services by train, coach and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Brindisi Airport.
- Coaches mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale).
- Travel with ITA, Air Dolomiti, Swiss to go to Brindisi by flight.
- Travel with Deutsche Bahn Intercity (DB IC) to go to Brindisi by train.
- Travel with FlixBus to go to Brindisi by coach.
Travelling from Frankfurt am Main to Brindisi: related information
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