Travel Information
Compare coach, train and flight for Florence to Domodossola
Omio recommends booking the train as it is the most popular option from Florence to Domodossola among Omio's users. If you are prioritising price, take the train, with an average ticket price of £34 For those with little time, consider booking a train, which has an average total journey time of 5h 17m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a train costs an average of £34, while a coach costs an average of £67.
Distance: 350 km
Compare train with
Most popular Train | Coach | Driving |
|---|---|---|
£34 Average Price Cheapest | £67 Average Price | £93 Average Price (fuel + tolls) |
5h 17m Average total duration Fastest 4h 47m Onboard + 30m Additional time* | 5h 24m Average total duration 4h 54m Onboard + 30m Additional time* | 4h 31m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.9kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | Your own car or car rental | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Florence to Domodossola:
A train is £33 less than a coach for this route with tickets for a coach from Florence to Domodossola costing on average £67.
A train is £131 less than a flight for this route with tickets for a flight from Florence to Domodossola costing on average £165.
Other travel options to Domodossola take longer:
Coach takes on average 5h 24m.
Flight takes on average 6h 26m.
Tickets start at around £34 compared to roughly £93 in fuel and tolls — a saving of about £59. The journey takes 4h 47m versus 4h 31m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Florence to Domodossola
How to get to Domodossola from Florence by train, bus, flight or ferry.
Our recommendation
The best way to travel from Florence to Domodossola is by taking a train because it’s the best combination of price and speed.
Regionale 17800 · Regionale Veloce TTPER 2460+
Autobus EC0424:329h48Florence Santa Maria Novella14:20Domodossola station£381One-way2 changes
Cheapest
Regionale 17800 · Regionale Veloce TTPER 2460+
Autobus EC0424:329h48Florence Santa Maria Novella14:20Domodossola station£381One-way2 changes
Fastest
AZ1684 · AZ205819:003h10Florence Peretola Airport22:10Milan Linate Airport£1571One-way1 change
Other options
9912+
Regionale Veloce 2028 · Regionale 114329:257h52Florence Santa Maria Novella17:17Domodossola station£431One-way2 changes
9916+
Regionale Veloce 2028 · Regionale 1143210:256h52Florence Santa Maria Novella17:17Domodossola station£471One-way2 changes
Intercity 580+
Autobus EC0648:217h59Florence Santa Maria Novella16:20Domodossola station£471One-way1 change
9912+
Autobus EC0429:254h55Florence Santa Maria Novella14:20Domodossola station£471One-way1 change
9912+
Autobus EC0649:256h55Florence Santa Maria Novella16:20Domodossola station£471One-way1 change
9912+
Autobus EC0669:259h55Florence Santa Maria Novella19:20Domodossola station£471One-way1 change
AZ1678 · AZ204411:203h50Florence Peretola Airport15:10Milan Linate Airport£1751One-way1 change
AZ1682 · AZ205615:304h40Florence Peretola Airport20:10Milan Linate Airport£1751One-way1 change
AZ1678 · AZ203811:204h50Florence Peretola Airport16:10Milan Linate Airport£1751One-way1 change
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
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FAQs: Florence to Domodossola
Travel to Domodossola easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Florence to Domodossola.

This is compared to other travel options from Florence to Domodossola:
A train is £33 less than a coach for this route with tickets for a coach from Florence to Domodossola costing on average £67.
A train is £131 less than a flight for this route with tickets for a flight from Florence to Domodossola costing on average £165.
Other travel options to Domodossola take longer:
Coach takes on average 5h 24m.
Flight takes on average 6h 26m.
- Around 15 flights per day.
- Around 12 trains per day.
- Around 5 coaches per day.
However, we recommend checking specific travel dates for your route between Florence and Domodossola as scheduled services by coach, train and flight can vary by season or day of the week.
- Flights mostly depart from Florence Peretola Airport and arrive in Milan Linate Airport.
- Trains mostly depart from Florence Santa Maria Novella and arrive in Domodossola station.
- Travel with Frecciarossa, Italo, Regionale, Intercity, Trenitalia, Intercity Notte to go to Domodossola by train.
- Travel with FlixBus to go to Domodossola by coach.
Travelling from Florence to Domodossola: related information
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