Travel Information
Compare train, coach and flight for Detroit, MI to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Detroit, MI to St. Louis, MO among Omio's users. If you are prioritising price, take the coach, with an average ticket price of £79 For those with little time, consider booking a flight, which has an average total journey time of 6h 29m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.7kg. Average ticket prices depend on the travel mode: a coach costs an average of £79, while a flight costs an average of £479.
Distance: 731 km
Compare train with
Most popular Train | Flight | Coach | Driving |
|---|---|---|---|
£166 Average Price | £479 Average Price | £79 Average Price Cheapest | £78 Average Price (fuel + tolls) |
10h 58m Average total duration 10h 28m Onboard + 30m Additional time* | 6h 29m Average total duration Fastest 4h 29m Onboard + 2h 0m Additional time* | 12h 43m Average total duration 12h 13m Onboard + 30m Additional time* | 7h 46m Average total duration (door-to-door) |
0.2 - 0.7kg CO2 emissions Lowest | 2.2 - 4.4kg CO2 emissions | 0.7 - 1.8kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Detroit, MI to St. Louis, MO:
A coach is £87 less than a train for this route with tickets for a train from Detroit, MI to St. Louis, MO costing on average £166.
A coach is £400 less than a flight for this route with tickets for a flight from Detroit, MI to St. Louis, MO costing on average £479.
Other travel options to St. Louis, MO take longer:
Train takes on average 10h 58m.
Coach takes on average 12h 43m.
You'll arrive about 3h 17m sooner (4h 29m by flight vs 7h 46m by car). Tickets start at around £479 compared to roughly £78 in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Detroit, MI to St. Louis, MO
How to get to St. Louis, MO from Detroit, MI by train, bus, flight or ferry.
Our recommendation
The best way to travel from Detroit, MI to St. Louis, MO is by taking a coach because it’s the best combination of price and speed.
+
FlixBus23:1517h25Detroit, Greyhound Terminal15:40St. Louis, S 15th St (Civic center)£671One-way1 change
Cheapest
+
FlixBus23:1517h25Detroit, Greyhound Terminal15:40St. Louis, S 15th St (Civic center)£671One-way1 change
Fastest
· 19:5513h00Detroit, Greyhound Terminal7:55St. Louis, S 15th St (Civic center)£671One-way1 change
Other options
· · 8:2015h55Detroit, Greyhound Terminal23:15St. Louis, S 15th St (Civic center)£681One-way2 changes
+
FlixBus16:2015h00Detroit, Greyhound Terminal6:20St. Louis, S 15th St (Civic center)£681One-way1 change
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, coaches, flights and ferries
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
09 Oct
10 Oct
11 Oct
12 Oct
13 Oct
14 Oct
15 Oct
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Detroit, MI to St. Louis, MO
Travel to St. Louis, MO easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Detroit, MI to St. Louis, MO.

This is compared to other travel options from Detroit, MI to St. Louis, MO:
A coach is £87 less than a train for this route with tickets for a train from Detroit, MI to St. Louis, MO costing on average £166.
A coach is £400 less than a flight for this route with tickets for a flight from Detroit, MI to St. Louis, MO costing on average £479.
Other travel options to St. Louis, MO take longer:
Train takes on average 10h 58m.
Coach takes on average 12h 43m.
- Around 46 flights per day.
- Around 4 coaches per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Detroit, MI and St. Louis, MO as scheduled services by train, coach and flight can vary by season or day of the week.
- Flights mostly depart from Detroit Wayne County Airport and arrive in St. Louis Lambert International Airport.
- Trains mostly depart from Detroit Amtrak, Detroit, MI and arrive in St. Louis Station, St. Louis, MO.
- Coaches mostly depart from Detroit, Greyhound Terminal and arrive in St. Louis, S 15th St (Civic center).
- Travel with Amtrak to go to St. Louis, MO by train.
- Travel with American Airlines, Republic Airlines, United, skywest airlines, Spirit Airlines, psa airlines to go to St. Louis, MO by flight.
- Travel with Greyhound, FlixBus to go to St. Louis, MO by coach.
- 0 direct flights per day with Spirit Airlines.
Travelling from Detroit, MI to St. Louis, MO: related information
Here are some other resources that might have the information you need


