How to get to St. Louis, MO from Detroit, MI

Mon 29 Dec
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Travel Information from Detroit, MI to St. Louis, MO

Distance453 miles
Available travel modesCoach, train or flight
Ticket price range£48 - £91
Cheapest modeCoach • £48 • 15 h
Fastest modeFlight • £91 • 4 h 33 min
Popular travel companiesGreyhound, American Airlines or Amtrak

Take a coach, train or flight to travel 453 miles from Detroit, MI to St. Louis, MO. The most popular travel providers which serve this trip are Greyhound, American Airlines or Amtrak among others. Travellers can even take a direct coach, flight or train from Detroit, MI to St. Louis, MO.

Travel options
from Detroit, MI to St. Louis, MO

How to get to St. Louis, MO from Detroit, MI by train, bus, flight or ferry.

Our recommendation

bus

The best way to travel from Detroit, MI to St. Louis, MO is by taking a coach because it’s the best combination of price and speed.

Greyhoundundefined · undefined
20:1512h40
Detroit, Greyhound Terminal
07:55St. Louis, S 15th St (Civic center)
£1421One-way
1 change

Cheapest

Greyhoundundefined · undefined
20:1512h40
Detroit, Greyhound Terminal
07:55St. Louis, S 15th St (Civic center)
£1421One-way
1 change

Fastest

UnitedUA3425 · UA4613
09:124h15
Detroit Wayne County Airport
12:27St. Louis Lambert International Airport
£3641One-way
1 change

Other options

Amtrak351 Wolverine · 21 Texas Eagle
06:2613h41
Detroit Amtrak, Detroit, MI
19:07St. Louis Station, St. Louis, MO
£2841One-way
1 change
Greyhoundundefined · undefined · undefined
23:2516h55
Detroit, Greyhound Terminal
15:20St. Louis, S 15th St (Civic center)
£1471One-way
2 changes
Greyhound+FlixBusFlixBus
16:2015h05
Detroit, Greyhound Terminal
06:25St. Louis, S 15th St (Civic center)
£1541One-way
1 change
Greyhound+FlixBusFlixBus
08:2015h50
Detroit, Greyhound Terminal
23:10St. Louis, S 15th St (Civic center)
£1831One-way
1 change
Sky West AirlinesAA6289 · AA5003
08:056h31
Detroit Wayne County Airport
13:36St. Louis Lambert International Airport
£3641One-way
1 change
psa airlinesAA5560+Republic AirlinesAA4595
12:484h35
Detroit Wayne County Airport
16:23St. Louis Lambert International Airport
£3641One-way
1 change
UnitedUA5381 · UA5873
13:564h58
Detroit Wayne County Airport
17:54St. Louis Lambert International Airport
£3641One-way
1 change

Find all the dates and times for this journey by train, bus, flight, and ferry .

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FAQs: Detroit, MI to St. Louis, MO

Travel to St. Louis, MO easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Detroit, MI to St. Louis, MO.

FAQs

There are 3 travel options to St. Louis, MO from Detroit, MI. You can take a coach, train or flight.

The cheapest way to go to St. Louis, MO from Detroit, MI is by taking a coach, which costs on average £48.

This is compared to other ways of getting from Detroit, MI to St. Louis, MO:

Taking a coach costs £44 less than taking a flight, which costs on average £91 for the same trip.

Taking a coach costs £20 less than taking a train, which costs on average £68 for the same trip.

The fastest way from Detroit, MI to St. Louis, MO is by flight with an average journey time of 4 h 33 min.

There are alternative travel options to St. Louis, MO that take longer:

Getting to St. Louis, MO by coach takes 15 h on average.

Getting to St. Louis, MO by train takes 13 h 41 min on average.

The Detroit, MI to St. Louis, MO distance is approximately 453 miles.

The average frequency per day from Detroit, MI to St. Louis, MO is:

  • Around 3 coaches per day.
  • Around 16 flights per day.
  • 2 trains a day.

However, we recommend checking specific travel dates for your route between Detroit, MI and St. Louis, MO as scheduled services by coach, train or flight can vary by season or day of the week.

These are the most popular departure and arrival points when travelling from Detroit, MI to St. Louis, MO:

    Omio works with many trusted partners that can help you travel the best way from Detroit, MI to St. Louis, MO:

    • You can go to St. Louis, MO from Detroit, MI by coach with Greyhound. You'll see cheap coach tickets for £58 with Greyhound from Detroit, MI to St. Louis, MO on Omio.
    • You can take a flight from Detroit, MI to St. Louis, MO with American Airlines. Cheap tickets can be found for £91 with American Airlines from Detroit, MI to St. Louis, MO.
    • You can travel by train from Detroit, MI to St. Louis, MO with Amtrak, and you can find Amtrak Detroit, MI to St. Louis, MO tickets for £68 on Omio.

    Yes, there are direct routes from Detroit, MI to St. Louis, MO with the following travel companies:

    • You can book a direct coach with.
    • You can travel directly by plane with.
    • You can book a direct train with.

    Direct services to St. Louis, MO tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your trip.

    Many of our customers travelling from Detroit, MI to St. Louis, MO don't make St. Louis, MO their final stop. Some of the destinations worth visiting after are Chicago, IL, Jefferson City, MO, Kansas City, KS, Joliet, IL or Rolla, MO, either of which you could add to your Detroit, MI and St. Louis, MO trip itinerary. Check Omio for the best and cheapest ways to travel from St. Louis, MO to any of these top destinations today!

    Travelling from Detroit, MI to St. Louis, MO: related information

    Here are some other resources that might have the information you need

    HomeTravelTravel to St. Louis, MOHow to get to St. Louis, MO from Detroit, MI

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