The cheapest and fastest trains from Venice Mestre to Karlsruhe Hbf
Cheapest price
£164
Average price
£164
Fastest journey
9 h 20 m
Average duration
9 h 20 m
Trains per day
1
Distance
486 km
The best way to find a cheap train ticket from Venice Mestre to Karlsruhe Hbf is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Venice Mestre to Karlsruhe Hbf will cost around £164 if you buy it on the day, but you can find cheap train tickets today for only £164.
To travel from Venice Mestre to Karlsruhe Hbf you need to make at least one change.


Travel Information
Compare train and coach for Venice Mestre to Karlsruhe Hbf
Omio recommends booking the coach as it is the most popular option from Venice Mestre to Karlsruhe Hbf among Omio's users. If you are prioritising price take the coach with prices starting from £48. For those with little time consider booking a train which can get you there in 10h 27m. The ticket price range depends on the travel mode: a coach costs an average of £48, and a train costs an average of £166.
Distance: 486 km
Compare train with
| Train | Most popular Coach |
|---|---|
£166 Average Price | £48 Average Price Cheapest |
10h 57m Average total duration Fastest 10h 27m Onboard + 30m Additional time* | 12h 42m Average total duration 12h 12m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Venice Mestre to Karlsruhe Hbf train times
The table below shows live departures for Venice Mestre to Karlsruhe Hbf trains for today, Wednesday 3 December. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 08:09 Venice Mestre | 9h20 | 17:29 Karlsruhe Hbf | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Venice Mestre to Karlsruhe Hbf by train or coach
Compare train and coach prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
04 Dec
05 Dec
06 Dec
07 Dec
08 Dec
09 Dec
10 Dec
Journey information
Overview: Train from Venice Mestre to Karlsruhe Hbf
Trains from Venice Mestre to Karlsruhe Hbf run on average 1 times per day, taking around 10h 27m. Cheap train tickets for this journey start at £166 but you can travel from only £48 by coach.
The earliest train runs at 08:09, the last at 08:09. The fastest train covers the 486 km distance in 9h 20m.
Distance 486 km |
Average train duration 10h 27m |
Cheapest ticket price £166 |
Trains per day 1 |
Fastest train 9h 20m |
First train 08:09 |
Last train 08:09 |
Train companies: Deutsche Bahn, Italo from Venice Mestre to Karlsruhe Hbf trainsDeutsche Bahn, Italo trains will get you between Venice Mestre and Karlsruhe Hbf from £48. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Italo
FAQs: Venice Mestre to Karlsruhe Hbf train
Find answers to the most common questions about traveling from Venice Mestre to Karlsruhe Hbf by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Karlsruhe Hbf, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Venice Mestre and Karlsruhe Hbf
- Mon - Sun: 05:50 - 20:30
- Provided by KiPoint and located on the ground floor.
- McDonald’s
- Chock Full O'Nuts
- Puro Gusto
- Juice Bar
- Rossosapore
- Full accessibility facilities, including toilets, ramps, wheelchairs, elevators and a mobility assistance center.
- Best Western Hotel Tritone
- The Plaza Hotel
- Hotel Villa Constanza
- Mon - Sun: 05:50 - 20:30
- Located in the main concourse.
- Bus lines: 2, 3, 10, 15, 18, 25a, 31, 31H, 32, 32H, 33H, 34H, 43, 53, 86, N1, 8AE
- Train lines: FR, FA, FB, EC, RJ, IC, EN, ICN, R, Italo
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
More options for your journey from Venice Mestre to Karlsruhe Hbf
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