- Recommended
Museo Regional de Antofagasta
Regional museum with archaeology, natural history and local heritage exhibits. A strong introduction to Antofagasta and the Atacama coast.
Flights from Santiago to Antofagasta depart on average 23 times per day, taking around 3h 11m. Cheap flight tickets for this journey start at £24 if you book in advance.
There are 15 flights per day. The earliest flight runs at 00:09, the last at 23:58. The fastest flight covers the 1091 km distance in 1h 58m. October is the cheapest month to fly.
Distance 1091 km |
Average flight duration 3h 11m |
Cheapest ticket price £24 |
Flights per day 23 |
Direct flights 15 |
Fastest flight 1h 58m |
First flight 0:09 |
Last flight 23:58 |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sept |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 21 days |
Cheapest price on 29 Sept
£23
Average ticket price on 29 Sept
£94
Fastest journey on 29 Sept
2 h 1 m
Average journey duration on 29 Sept
2 h 2 m
Flights on 29 Sept
6
Distance
1091 km
The best way to find a cheap flight ticket from Santiago to Antofagasta is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santiago to Antofagasta will cost around £94 if you buy it on the day, but you can find cheap flight tickets today for only £23.
On Tue 29 Sept, we found 6 flights from Santiago to Antofagasta, including 6 direct services.
These direct flights cover the 1091 km distance in an average of 2 h 2 m but if you time it right, some flights will get you there in just 2 h 1 m .
The slowest flights will take 2 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










The table below shows live departures for Santiago to Antofagasta flights for today, Monday 28 September. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 8:06 Santiago | 2h04 | 10:10 Antofagasta | 0 changesdirect | |
![]() | 9:14 Santiago | 2h05 | 11:19 Antofagasta | 0 changesdirect | |
![]() | 9:15 Santiago | 2h04 | 11:19 Antofagasta | 0 changesdirect | |
![]() | 20:18 Santiago | 2h00 | 22:18 Antofagasta | 0 changesdirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Antofagasta — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Antofagasta trip today.
Regional museum with archaeology, natural history and local heritage exhibits. A strong introduction to Antofagasta and the Atacama coast.
Museum focused on desert minerals and mining culture. A practical stop for understanding the region’s geology and economic history.
Railway museum with locomotives, carriages and industrial artefacts. It highlights the rail links that shaped northern Chile.
Long urban beach promenade for walking, sunsets and sea views. It is one of the city’s most pleasant public spaces for a relaxed stroll.
Central square surrounded by key civic buildings and palms. A convenient base for seeing the cathedral, clock tower and daily city life.
Seaside pedestrian area by the port with public art and broad views. It is a popular place for an evening walk in the city centre.
Northern Chilean ceviche of fresh local fish cured in lime with onion and coriander. A classic coastal dish that reflects Antofagasta’s Pacific seafood culture.
Cold shellfish broth with lemon, onion and coriander, often made with clams or mixed seafood. Traditional on Chile’s coast and especially popular in the north.
A hearty seafood soup with fish, shellfish, stock and vegetables. It is a staple in Chilean marisquerías and showcases the rich catch landed on the Antofagasta coast.
Established seafood restaurant known for ceviche, paila marina and classic Chilean fish dishes in a relaxed, coastal-style setting.
Well-known restaurant for grilled seafood, fish and Chilean specialities, with broad sea views and a polished but approachable atmosphere.
Popular casual venue for sushi, Nikkei-influenced seafood and cocktails, suited to diners wanting a modern option in Antofagasta.
Moderate for Chilean cities. Hotels in mining season can be pricey, but everyday dining and local buses stay fairly manageable for visitors.
Restaurants often add a voluntary 10% service charge; leave it if service is good. Round up in cafés. Taxis do not require tips, but rounding up the fare is common.
Official public transport app
Aeropuerto Andrés Sabella -> Plaza Colón, Antofagasta
Find answers to the most common questions about traveling from Santiago to Antofagasta by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Antofagasta, this guide helps you travel smarter and with confidence.

Most Santiago to Antofagasta flights use the Santiago to Antofagasta airport pair. Use this guide to compare Santiago and Antofagasta airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Santiago is 8 km from Santiago city centre. Public transport options include:
Santiago has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office and Car Rental.
Food options include: Restaurants available in both domestic and intertiol terminals; options include fast food and Chilean cuisine.
Free Wi-Fi available throughout the airport. ATMs are located in both domestic and intertiol terminals.
Lost and found is available at the station.
Available at Santiago: Parking, Taxis, WC.
Available at Santiago: Car Rental.
Accessibility facilities are available at Santiago: Elevators, ramps.
Nearby hotels include Hotels nearby include Holiday Inn Santiago Airport, within walking distance..
Antofagasta is 23 km from Antofagasta city centre. Public transport options include:
Antofagasta has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Lounge, Lost and Found Office and Car Rental.
Food options include: Several restaurants and cafes are located in the main terminal, offering local and intertiol cuisine.
Free Wi-Fi available throughout the airport. ATMs are located in the arrivals and departures areas.
Lost and found is available at the station.
Available at Antofagasta: Parking, Taxis, WC.
Available at Antofagasta: Car Rental.
Accessibility facilities are available at Antofagasta: Elevators, ramps.
Here are some other resources that might have the information you need