- Must visit
Archaeological Museum of Mytilene
Archaeological museum with mosaics, sculpture and finds from ancient Lesbos. Essential for understanding the island’s long history.
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Journey information
Overview: Ferry from Santorini (Island) to Mytilene
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Take a ferry from Santorini (Island) to Mytilene and enjoy the approximately 171 nautical miles (317 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £102
Distance 171 nautical miles (317 km) |
High Season Jul - Sept |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £102
Complete guide to Mytilene
Things to do in Mytilene
Discover the best of Mytilene — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mytilene trip today.
- Recommended
Museum of Industrial Olive-Oil Production of Lesvos
Former industrial olive-oil site presenting Lesbos’s production history with machinery and exhibits. Insightful and distinctive local heritage museum.
- Recommended
Theophilos Museum
Compact museum devoted to Theophilos, showing works linked to Greek folk painting and island life. A rewarding stop for art lovers.
- Must visit
Epano Skala
Historic harbour district with narrow lanes, old houses and sea views. Popular for walking and getting a feel for traditional Mytilene.
- Recommended
Sappho Square
Central square lined with civic buildings and daily city life. A practical and atmospheric base for exploring the old centre on foot.
- Recommended
Ermou Street
Main shopping and strolling street with arcades, local shops and lively urban character. Ideal for an easy walk through the heart of town.
- Gluten-free
Sardeles Kallonis
Salt-cured sardines from the Gulf of Kalloni, prized on Lesvos for their rich flavour and long fishing tradition. Usually served simply with lemon and olive oil.
- Vegetarian
- Vegan
- Gluten-free
Ouzo Plomari
Anise-flavoured spirit closely associated with Lesvos, especially Plomari. It is the island’s signature drink and a classic companion to meze.
- Gluten-free
Chtapodi sta Karvouna
Local meze of grilled or pan-fried octopus, common in seaside tavernas. It reflects the island’s strong fishing culture and Aegean flavours.
Martano
Refined restaurant serving modern Greek cooking with local ingredients in an elegant harbourfront setting suited to a longer evening meal.
To Kastro
Popular traditional taverna known for Lesvian meze, seafood and ouzo in a relaxed local setting near the waterfront.
Kalnterimi
Established fish taverna focusing on fresh seafood and classic island dishes, with a straightforward atmosphere favoured by locals and visitors.
Euro (€)
Moderate for Greece: tavernas and buses are reasonable, but summer rooms and seafront dining cost more than on less touristy islands.
Average meal costs
- Budget
- €8-12 for fast food or simple souvlaki.
- Mid-range
- €18-30 per person for a restaurant meal.
- Fine dining
- €45-70 per person for upscale dining.
- Coffee
- €2.50-4 for cappuccino or iced coffee.
Tipping culture
Service is usually included. Round up or leave 5-10% in restaurants for good service; round up taxi fares; small change is fine in cafés.
FAQs: Santorini (Island) to Mytilene ferries
Find answers to the most common questions about traveling from Santorini (Island) to Mytilene by ferry. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest ferry, the cheapest option, or tips for making the most of your visit at Mytilene, this guide helps you travel smarter and with confidence.
Yes, you can take a flight between Santorini (Island) and Mytilene.
Most popular ferries to and from Mytilene and Santorini (Island)
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