The cheapest and fastest trains from Mendrisio to Karlsruhe
Cheapest price
£121
Average price
£121
Fastest journey
5 h 25 m
Average duration
5 h 25 m
Trains per day
1
Distance
352 km
The best way to find a cheap train ticket from Mendrisio to Karlsruhe is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Mendrisio to Karlsruhe will cost around £121 if you buy it on the day, but you can find cheap train tickets today for only £121.
To travel from Mendrisio to Karlsruhe you need to make at least one change.
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Travel Information
Compare train, coach and flight for Mendrisio to Karlsruhe
Omio recommends booking the flight as it is the most popular option from Mendrisio to Karlsruhe among Omio's users. If you are prioritising price take the coach with prices starting from £22. For those with little time consider booking a flight which can get you there in 1h 10m. The ticket price range depends on the travel mode: a coach costs an average of £22, and a train costs an average of £122.
Distance: 352 km
Compare train with
| Train | Most popular Flight | Coach |
|---|---|---|
£122 Average Price | £65 Average Price | £30 Average Price Cheapest |
5h 55m Average total duration 5h 25m Onboard + 30m Additional time* | 4h 10m Average total duration Fastest 1h 10m Onboard + 3h 0m Additional time* | 11h 14m Average total duration 10h 44m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Mendrisio to Karlsruhe train times
The table below shows live departures for Mendrisio to Karlsruhe trains for today, Sunday 14 December. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 12:04 Mendrisio | 5h25 | 17:29 Karlsruhe | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mendrisio to Karlsruhe by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
15 Dec
16 Dec
17 Dec
18 Dec
19 Dec
20 Dec
21 Dec
Journey information
Overview: Train from Mendrisio to Karlsruhe
Trains from Mendrisio to Karlsruhe run on average 1 times per day, taking around 5h 25m. Cheap train tickets for this journey start at £122 but you can travel from only £22 by coach.
The earliest train runs at 12:04, the last at 12:04. The fastest train covers the 352 km distance in 5h 25m.
Distance 352 km |
Average train duration 5h 25m |
Cheapest ticket price £122 |
Trains per day 1 |
Fastest train 5h 25m |
First train 12:04 |
Last train 12:04 |
Train companies: Swiss Railways (SBB/CFF/FFS) from Mendrisio to Karlsruhe trainsSwiss Railways (SBB/CFF/FFS) trains will get you between Mendrisio and Karlsruhe from £22. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Swiss Railways (SBB/CFF/FFS)
FAQs: Mendrisio to Karlsruhe train
Find answers to the most common questions about traveling from Mendrisio to Karlsruhe by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Mendrisio and Karlsruhe
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available 24/7 in the nearby parking lot.
- Ristorante Pizzeria Corona
- Osteria Lanterna
- Outside the main entrance.
- Ramps, restrooms.
- CHF 1
- Hotel Coronado
- Albergo Stazione Mendrisio
- Hotel Milano
- Located in the main hall
- 200 places, covered
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-3 for trains to Italy and regional destinations
- Train: S10, S40
- Bus: Several lines available
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
Most popular train connections from Mendrisio
More options for your journey from Mendrisio to Karlsruhe
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