The cheapest and fastest trains from Mendrisio to Karlsruhe
Cheapest price
£111
Average price
£111
Fastest journey
5 h 25 m
Average duration
5 h 25 m
Trains per day
1
Distance
352 km
The best way to find a cheap train ticket from Mendrisio to Karlsruhe is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Mendrisio to Karlsruhe will cost around £111 if you buy it on the day, but you can find cheap train tickets today for only £111.
To travel from Mendrisio to Karlsruhe you need to make at least one change.


Live departures
Mendrisio to Karlsruhe train times
The table below shows live departures for Mendrisio to Karlsruhe trains for tomorrow, Friday 20 March. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 12:04 Mendrisio | 5h25 | 17:29 Karlsruhe | 1 change | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mendrisio to Karlsruhe by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Mendrisio to Karlsruhe
Trains from Mendrisio to Karlsruhe run on average 1 times per day, taking around 5h 25m. Cheap train tickets for this journey start at £111 if you book in advance.
The earliest train runs at 12:04, the last at 12:04. The fastest train covers the 352 km distance in 5h 25m.
Distance 352 km |
Average train duration 5h 25m |
Cheapest ticket price £111 |
Trains per day 1 |
Fastest train 5h 25m |
First train 12:04 |
Last train 12:04 |
Train companies: Trenord from Mendrisio to Karlsruhe trainsTrenord trains will get you between Mendrisio and Karlsruhe from £111. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenord
FAQs: Mendrisio to Karlsruhe train
Find answers to the most common questions about traveling from Mendrisio to Karlsruhe by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Mendrisio and Karlsruhe
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available 24/7 in the nearby parking lot.
- Ristorante Pizzeria Corona
- Osteria Lanterna
- Outside the main entrance.
- Ramps, restrooms.
- CHF 1
- Hotel Coronado
- Albergo Stazione Mendrisio
- Hotel Milano
- Located in the main hall
- 200 places, covered
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-3 for trains to Italy and regional destinations
- Train: S10, S40
- Bus: Several lines available
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
Most popular train connections from Mendrisio
More options for your journey from Mendrisio to Karlsruhe
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