Travel Information
Compare train, coach and flight for Mainz to Plzeň
Omio recommends booking the train as it is the most popular option from Mainz to Plzeň among Omio's users. If you are prioritising price take the coach with prices starting from £35. For those with little time consider booking a coach which can get you there in 5h 25m. The ticket price range depends on the travel mode: a coach costs an average of £35, and a flight costs an average of £123.
Distance: 366 km
Compare train with
Most popular Train | Flight | Coach |
|---|---|---|
£45 Average Price | £134 Average Price | £35 Average Price Cheapest |
6h 25m Average total duration 5h 55m Onboard + 30m Additional time* | 8h 55m Average total duration 5h 55m Onboard + 3h 0m Additional time* | 5h 55m Average total duration Fastest 5h 25m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Mainz to Plzeň by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
06 Nov
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Journey information
Overview: Train from Mainz to Plzeň
Trains from Mainz to Plzeň run on average 6 times per day, taking around 5h 55m. Cheap train tickets for this journey start at £41 but you can travel from only £35 by coach.
The earliest train runs at 06:05, the last at 22:05. The fastest train covers the 366 km distance in 6h 10m.
Distance 366 km |
Average train duration 5h 55m |
Cheapest ticket price £41 |
Trains per day 6 |
Fastest train 6h 10m |
First train 06:05 |
Last train 22:05 |
Train companies: Deutsche Bahn, Süwex, vlexx from Mainz to Plzeň trainsDeutsche Bahn, Süwex, vlexx trains will get you between Mainz and Plzeň from £35. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Süwex
vlexx
FAQs: Mainz to Plzeň train
Find answers to the most common questions about traveling from Mainz to Plzeň by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Plzeň, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Mainz and Plzeň
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
- McDonald's
- Cafe Extrablatt
- Hans im Glück
- The Big Easy
- Hyatt Regency Mainz
- Favorite Parkhotel
- Ibis Hotel Mainz City
- Hof Ehrenfels
- 5:00 AM - 11:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 1:00 a.m. Departures can be made outside of opening hours. Access via Nádražní street.
- Restaurant Na Spilce
- U Salzmannů
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Hotel Central
- Courtyard by Marriott Pilsen
- Hotel Victoria
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-6 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket offices and waiting area
- Tram: Line 1, Line 2
- Bus: Several lines available
Most popular train connections from Mainz
More options for your journey from Mainz to Plzeň
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