The cheapest and fastest trains from Genoa Brignole to Palermo Centrale
Cheapest price
£51
Average price
£77
Fastest journey
20 h 15 m
Average duration
21 h 17 m
Trains per day
2
Distance
792 km
The best way to find a cheap train ticket from Genoa Brignole to Palermo Centrale is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Genoa Brignole to Palermo Centrale will cost around £77 if you buy it on the day, but you can find cheap train tickets today for only £51.
Of the 2 trains that leave Genoa Brignole for Palermo Centrale every day 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct trains cover the 792 km distance in an average of 21 h 17 m but if you time it right, some trains will get you there in just 20 h 15 m .
The slowest trains will take 22 h 19 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, coach, flight and ferry for Genoa Brignole to Palermo Centrale
Omio recommends booking the train as it is the most popular option from Genoa Brignole to Palermo Centrale among Omio's users. If you are prioritising price take the flight with prices starting from £20. For those with little time consider booking a flight which can get you there in 1h 50m. The ticket price range depends on the travel mode: a flight costs an average of £20, and a train costs an average of £42.
Distance: 792 km
Compare train with
Most popular Train | Flight | Ferry | Coach |
|---|---|---|---|
£83 Average Price | £52 Average Price Cheapest | £64 Average Price | £74 Average Price |
17h 12m Average total duration 16h 42m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* | 21h 16m Average total duration 20h 16m Onboard + 1h 0m Additional time* | 28h 31m Average total duration 28h 1m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options | Direct Options |
Live departures
Genoa Brignole to Palermo Centrale train times
The table below shows live departures for Genoa Brignole to Palermo Centrale trains for today, Monday 8 December. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 17:08 Genoa Brignole | 25h54 | 19:02 Palermo Centrale | 3 changes | |
| Tuesday 9 December | |||||
![]() | 10:33 Genoa Brignole | 22h19 | 08:52 Palermo Centrale | 0 changesdirect | |
![]() | 15:17 Genoa Brignole | 20h15 | 11:32 Palermo Centrale | 0 changesdirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Genoa Brignole to Palermo Centrale by train, coach, flight or ferry
Compare train, coach, flight and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
09 Dec
10 Dec
11 Dec
12 Dec
13 Dec
14 Dec
15 Dec
Journey information
Overview: Train from Genoa Brignole to Palermo Centrale
Trains from Genoa Brignole to Palermo Centrale run on average 6 times per day, taking around 16h 42m. Cheap train tickets for this journey start at £42 but you can travel from only £20 by flight.
The earliest train runs at 10:33, the last at 20:59. The fastest train covers the 792 km distance in 17h 15m.
Distance 792 km |
Average train duration 16h 42m |
Cheapest ticket price £42 |
Trains per day 6 |
Fastest train 17h 15m |
First train 10:33 |
Last train 20:59 |
Train companies: Intercity Notte, Intercity, Frecciarossa, Regionale from Genoa Brignole to Palermo Centrale trainsIntercity Notte, Intercity, Frecciarossa, Regionale trains will get you between Genoa Brignole and Palermo Centrale from £20. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Intercity
Frecciarossa
Regionale
FAQs: Genoa Brignole to Palermo Centrale train
Find answers to the most common questions about traveling from Genoa Brignole to Palermo Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Genoa Brignole and Palermo Centrale
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, with access from Piazza Verdi.
- Ristorante Pizzeria da Toto
- Trattoria Rosmarino
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Bristol Palace
- NH Genova Centro
- Best Western Hotel Moderno Verdi
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-3 for regional trains
- Hall 2: platform 4-6 for intercity trains
- Hall 3: platform 7-9 for high-speed trains
- Metro: Line M
- Bus: Several lines available
- Tram: Line 12
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