Pisa to Brussels bus with FlixBus

Thu 14 May
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FlixBus
National Express
Alsa
Flibco
BlaBlaCar Bus
2,000+ travel companies
FlixBus
National Express
Alsa
Flibco
BlaBlaCar Bus
2,000+ travel companies
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The cheapest and fastest coaches from Pisa to Brussels

Showing times and prices for 14 May

Cheapest price

£101

Average price

£105

Fastest journey

1 d 1 h 50 m

Average duration

1 d 2 h 58 m

Buses per day

4

Distance

914 km

Cheap tickets

The best way to find a cheap coach ticket from Pisa to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.

The average ticket from Pisa to Brussels will cost around £105 if you buy it on the day, but you can find cheap coach tickets today for only £101.

Fast coaches

To travel from Pisa to Brussels you need to make at least 2 changes.

  • FlixBusFlixBus · FlixBus · FlixBus
    13:5028h05
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    17:55Brussels, Brussels South (Gare du Midi)
    £1011One-way
    2 changes
  • FlixBusFlixBus · FlixBus · FlixBus
    9:4027h05
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    12:45Brussels, Brussels South (Gare du Midi)
    £1061One-way
    2 changes
  • FlixBusFlixBus · FlixBus · FlixBus
    16:4526h50
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    19:35Brussels, Brussels South (Gare du Midi)
    £1061One-way
    2 changes
  • FlixBusFlixBus · FlixBus · FlixBus
    6:2525h50
    Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
    8:15Brussels, Brussels South (Gare du Midi)
    £1091One-way
    2 changes

Travel Information

Compare train, coach and flight for Pisa to Brussels

Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from £17. For those with little time consider booking a flight which can get you there in 2h 31m. In case you are seeking to minimise your carbon footprint the coach is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a flight costs an average of £17, and a train costs an average of £207.

Distance: 914 km

Compare bus with

Coach
Most popular
Flight
Train

£100

Average Price

£99

Average Price

Cheapest

£275

Average Price

21h 28m

Average total duration

20h 58m

Onboard

+

30m

Additional time*

5h 31m

Average total duration

Fastest

2h 31m

Onboard

+

3h 0m

Additional time*

19h 50m

Average total duration

19h 20m

Onboard

+

30m

Additional time*

0.9 - 2.3kg

CO2 emissions

Lowest

2.7 - 5.5kg

CO2 emissions

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Pisa to Brussels bus times

The table below shows live departures for Pisa to Brussels coaches for today, Wednesday 13 May. You can also manually refresh the results below to see updated coach journeys.

Last updated at
ProviderDepartsDurationArrivesChanges
Tickets
FlixBusFlixBus · FlixBus · FlixBus23:30 Pisa, Aeroporto Parcheggio Aurelia
32h45
8:15 Brussels, Brussels South (Gare du Midi)2 changes
Thursday 14 May
FlixBusFlixBus · FlixBus · FlixBus6:25 Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
25h50
8:15 Brussels, Brussels South (Gare du Midi)2 changes
FlixBusFlixBus · FlixBus · FlixBus9:40 Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
27h05
12:45 Brussels, Brussels South (Gare du Midi)2 changes

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Pisa to Brussels by train, coach or flight

Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
14 May
Fri
15 May
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16 May
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03 Jun

Why should you book Pisa to Brussels coaches with Omio?

FlixBus operates all coaches services from Pisa to Brussels.
Omio is an official ticket reseller for all your travel options from Pisa to Brussels.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Brussels.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Brussels.

Journey information

Overview: Bus from Pisa to Brussels

ItalyItaly
BelgiumBelgium
Icon of bus

Buses from Pisa to Brussels run on average 4 times per day, taking around 20h 58m. Cheap bus tickets for this journey start at £59 but you can travel from only £17 by flight.

The earliest coach runs at 01:30, the last at 23:45. The fastest coach covers the 914 km distance in 25h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £17
Distance
914 km
Average bus duration
20h 58m
Cheapest ticket price
£59
Buses per day
4
Fastest bus
25h 10m
First bus
1:30
Last bus
23:45
Cheapest Month
Jul
Cheapest Day
Tue
High Season
Oct - Dec
Low Season
Jan - Mar
Busiest Day
Wed
Least Busy Day
Fri
Best time to book
42 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from £17

Bus providers: FlixBus from Pisa to BrusselsYou can travel by bus between Pisa to Brussels with FlixBus for as low as £17. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
25h 10m
Cheapest Price
£59
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Pisa to Brussels coach

Find answers to the most common questions about traveling from Pisa to Brussels by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Pisa to Brussels can start from as little as £59 when you book in advance. The average coach ticket price for Pisa to Brussels is £100; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Pisa to Brussels is 25h 10m to travel the 914 km long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Pisa to Brussels leaves at 1:30. Plan your trip with the Journey Planner from Omio.
The latest coach from Pisa to Brussels leaves at 23:45.
There are 4 coaches a day from Pisa to Brussels which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer coaches.
When taking a coach from Pisa to Brussels, you can count on FlixBus for the best way to get you to Brussels. You can also check all possible coach companies who offer a service between Pisa and Brussels and compare the amenities they offer before buying a coach ticket.
When departing from Pisa , you have various coach station options to start your route from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa, Aeroporto Parcheggio Aurelia, Lucca, Viale Regina Margherita / Via Montanara . When arriving in Brussels , you can end your route in coach stations like Brussels, Brussels South (Gare du Midi), Brussels, Gare Du Midi, Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord), Bruxelles, Gare du Nord.Passengers board the coach most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 away from the city centre, and they get off the coach at Brussels, Brussels South (Gare du Midi), located 2 away from the city centre.
A trip to Brussels from Pisa is worth doing but not as a day trip with a journey time of 25h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Pisa to Brussels is July.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Brussels including taking a train, coach and flight.
Yes, the following accessibility options are available when taking the coach from Pisa to Brussels:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the coach from Pisa to Brussels for coach company FlixBus.
Whether you can cancel your coach ticket from Pisa to Brussels depends on the coach companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Pisa to Brussels.
Yes, the following luggage options are included when booking a coach ticket from Pisa to Brussels:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Pisa to Brussels:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Pisa to Brussels. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the coach from Pisa to Brussels with the following coach company: FlixBus
Yes, there are USB plugs on board the coach from Pisa to Brussels with the following coach company: FlixBus.
Yes, there is Wifi on board the coach from Pisa to Brussels with the following coach company: FlixBus.

popular bus stations

Important Stations and Airports in Pisa and Brussels

Pisa
Brussels
The major coach station for departures in Pisa is Pisa, Via delle Fiamme Gialle (Park Pietrasantina). Find all the information you need to know about services, amenities and connections at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) for your trip from Pisa to Brussels.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Pisa, Aeroporto Parcheggio Aurelia
information

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