The cheapest and fastest coaches from Brindisi to Siena
Cheapest price
£71
Average price
£84
Fastest journey
11 h 15 m
Average duration
11 h 53 m
Buses per day
11
Distance
622 km
The best way to find a cheap coach ticket from Brindisi to Siena is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Brindisi to Siena will cost around £84 if you buy it on the day, but you can find cheap coach tickets today for only £71.
Of the 11 buses that leave Brindisi for Siena every day 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 622 km distance in an average of 11 h 53 m but if you time it right, some buses will get you there in just 11 h 15 m .
The slowest buses will take 12 h 34 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
107
1104 · 2494
206
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
206
FlixBus · FlixBus
107
FlixBus · FlixBus
1104 · 2494Travel Information
Compare coach, train and flight for Brindisi to Siena
Omio recommends booking the coach as it is the most popular option from Brindisi to Siena among Omio's users. If you are prioritising price take the coach with prices starting from £14. For those with little time consider booking a flight which can get you there in 2h 36m. The ticket price range depends on the travel mode: a coach costs an average of £14, and a flight costs an average of £26.
Distance: 622 km
Compare bus with
Most popular Coach | Train | Flight |
|---|---|---|
£37 Average Price Cheapest | £78 Average Price | £102 Average Price |
11h 34m Average total duration 11h 4m Onboard + 30m Additional time* | 10h 25m Average total duration 9h 55m Onboard + 30m Additional time* | 5h 36m Average total duration Fastest 2h 36m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Brindisi to Siena bus times
The table below shows live departures for Brindisi to Siena coaches for today, Sunday 9 November. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
1120 | 04:30 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 10h35 | 15:05 Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 changesdirect | |
206 | 04:35 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 11h15 | 15:50 Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 changesdirect | |
FlixBus · FlixBus | 08:55 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h00 | 21:55 Siena, P.za Gramsc | 1 change | |
FlixBus · FlixBus | 08:55 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 11h45 | 20:40 Siena, Siena/Viale Pietro Toselli | 1 change | |
FlixBus · FlixBus | 08:55 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 11h55 | 20:50 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
FlixBus · FlixBus | 09:35 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h05 | 23:40 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
1104 · 2494 | 11:30 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 12h34 | 00:04 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
FlixBus · FlixBus · FlixBus | 11:40 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 16h50 | 04:30 Siena, Stazione FS (Piazzale Carlo Rosselli) | 2 changes | |
FlixBus · FlixBus · FlixBus | 15:35 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 15h45 | 07:20 Siena, Siena/Viale Pietro Toselli | 2 changes | |
2204 · 1121 | 16:50 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 15h05 | 07:55 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
107 | 19:50 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 11h55 | 07:45 Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 changesdirect | |
FlixBus · FlixBus | 20:30 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h05 | 09:35 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
FlixBus · FlixBus | 22:30 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 15h20 | 13:50 Siena, Siena/Viale Pietro Toselli | 1 change | |
FlixBus · FlixBus | 22:30 Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 11h45 | 10:15 Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brindisi to Siena by coach, train or flight
Compare coach, train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
10 Nov
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16 Nov
Journey information
Overview: Bus from Brindisi to Siena
Buses from Brindisi to Siena run on average 12 times per day, taking around 11h 4m. Cheap bus tickets for this journey start at £14 if you book in advance.
There are 2 coaches per day. The earliest coach runs at 00:05, the last at 23:39. The fastest coach covers the 622 km distance in 10h 35m.
Distance 622 km |
Average bus duration 11h 4m |
Cheapest ticket price £14 |
Buses per day 12 |
Direct buses 2 |
Fastest bus 10h 35m |
First bus 00:05 |
Last bus 23:39 |
Bus providers: Marino Autolinee, FlixBus from Brindisi to SienaYou can travel by bus between Brindisi to Siena with Marino Autolinee, FlixBus for as low as £14. When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
FlixBus
FAQs: Brindisi to Siena coach
Find answers to the most common questions about traveling from Brindisi to Siena by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

Passengers board the coach most frequently from Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), which is located around 0.6 miles (1 km) away from the city centre, and they get off the coach at Siena, Stazione FS (Piazzale Carlo Rosselli), located 1.5 miles (2.4 km) away from the city centre.
To find the cheapest bus tickets for your trip from Brindisi to Siena, follow these tips:
Start your search now and compare ticket prices to find the best deal!
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