Travel Information
Compare coach and train for Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf
Omio recommends booking the train as it is the most popular option from Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf among Omio's users. If you are prioritising price take the coach with prices starting from £41. For those with little time consider booking a train which can get you there in 4h 34m. The ticket price range depends on the travel mode: a coach costs an average of £41, and a train costs an average of £69.
Distance: 394 km
Compare train with
Most popular Train | Coach |
|---|---|
£69 Average Price | £41 Average Price Cheapest |
5h 4m Average total duration Fastest 4h 34m Onboard + 30m Additional time* | 7h 7m Average total duration 6h 37m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf train times
The table below shows live departures for Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf trains for today, Wednesday 25 February. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
![]() | 04:27 Hamburg, Hauptbahnhof/Spitalerstraße | 3h47 | 08:14 Frankfurt (Main) Hbf | 0 changesdirect | |
![]() | 05:29 Hamburg, Hauptbahnhof/Spitalerstraße | 3h45 | 09:14 Frankfurt (Main) Hbf | 0 changesdirect | |
![]() | 06:23 Hamburg, Hauptbahnhof/Spitalerstraße | 3h33 | 09:56 Frankfurt (Main) Hbf | 0 changesdirect | |
![]() | 06:29 Hamburg, Hauptbahnhof/Spitalerstraße | 3h45 | 10:14 Frankfurt (Main) Hbf | 0 changesdirect | |
![]() | 07:29 Hamburg, Hauptbahnhof/Spitalerstraße | 3h45 | 11:14 Frankfurt (Main) Hbf | 0 changesdirect |
Find all the dates and times for this journey
Compare prices and tickets Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf by coach or train
Compare coach and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
26 Feb
27 Feb
28 Feb
01 Mar
02 Mar
03 Mar
04 Mar
Why should you book Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of Deutsche Bahn Intercity (DB IC) to find the best option for your trip from Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus and train to ensure you get the best deal for traveling from Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf.
Why book with Omio over Trainline or Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf.
Journey information
Overview: Train from Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf
Trains from Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf run on average 18 times per day, taking around 4h 34m. Cheap train tickets for this journey start at £69 but you can travel from only £41 by coach.
There are 7 trains per day. The earliest train runs at 04:27, the last at 22:45. The fastest train covers the 394 km distance in 3h 33m.
Distance 394 km |
Average train duration 4h 34m |
Cheapest ticket price £69 |
Trains per day 18 |
Direct trains 7 |
Fastest train 3h 33m |
First train 04:27 |
Last train 22:45 |
Train companies: Deutsche Bahn, Deutsche Bahn Intercity (DB IC) from Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf trainsDeutsche Bahn, Deutsche Bahn Intercity (DB IC) trains will get you between Hamburg, Hauptbahnhof/Spitalerstraße and Frankfurt (Main) Hbf from £41. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Deutsche Bahn Intercity (DB IC)
FAQs: Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf train
Find answers to the most common questions about traveling from Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt (Main) Hbf, this guide helps you travel smarter and with confidence.

popular train stations
Important Stations and Airports in Hamburg, Hauptbahnhof/Spitalerstraße and Frankfurt (Main) Hbf
- Mon - Fri: 07:00 - 21:00
- Sat - Sun: 09:00 - 21:00
- Free Wi-Fi in the station.
- Luggage lockers are located in the main hall.
- asiagourmet
- Burger King
- Ciao Bella
- Coffee Fellows
- Crepes de France Express
- dean&david
- Starbucks
- Uddin's Sky Sportsbar
- McDonald's
- Dunkin Donuts
- & many more
- Step-free access and step markings. Contact the Mobility Service Centre at +49 3065212888 or [email protected].
- Hotel Cristall
- Grand Hotel Empire
- Hotel Carlton
- Located opposite Platforms 12 and 13.
More options for your journey from Hamburg, Hauptbahnhof/Spitalerstraße to Frankfurt (Main) Hbf
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